Experimental Study on the Effect of Fibrin Sealant in Renal Surgery

Kwon, Sung Won; Park, Young Yo

Abstract

The most serious complications of renal surgery, such as nephrotomy or partial nephrectomy, are intraoperative bleeding, urine leakage or secondary hemorrhage. To avoid such complication, meticulous parenchymal sutures are necessary with traumatizing loss of renal functioning parenchyma. Fibrin sealant is a newly developed substance for hemostasis, tissue sealing and wound healing. We made the experimental study on the effect of fibrin sealant in renal surgery to minimize to above complications without sutures. The following results were obtained: 1. The fibrin sealant was useful for joining the wound surfaces in nephrotomy or partial nephrectomy. 2. The serious complications, such as hemorrhage or urine leakage could be reduced. 3. The significant parenchymal loss caused by sutures was eliminated by its applications. 4. There was no foreign body reaction with its applications. Judging from the results of this experiments, it may be expected that by the use of the fibrin sealant the surgical complications can be markedly reducible in urologic surgical fields.