J Korean Ophthalmol Soc.  2005 Jun;46(6):995-999.

Fibrin Sealant Injection for Control of Hemorrhage in Vitreous Surgery of Proliferative Diabetic Retinopathy

Affiliations
  • 1Department of Ophthalmology, Eulji University School of Medicine, Seoul, Korea. pjs4106@eulji.or.kr

Abstract

PURPOSE
To study the effectiveness of fibrin sealant to control intraoperative bleeding during pars plana vitrectomy of proliferative diabetic retinopathy. METHODS: Intravitreal fibrin sealant was applied to 100 eyes of proliferative diabetic retinopathy patients prospectively. Preoperative fundus finding included longstanding vitreous hemmorrhages, preretinal macular hemorrhages and tractional retinal detachments. The male vs female ratio was 38: 52, and the mean age was 62.4 years. Panretinal laser photocoagulation was done in all patients preoperatively. RESULTS: In all of 100 (100%) eyes, intraoperative bleeding was controled. Intraoperative complication consisted overinjection of fibrin sealant in 2 eyes. Postoperative complications comprised transient IOP elevation in 20 eyes, mild epiretinal membrane in 1 eye, and delayed absorption of fibrin sealant in 1 eye. Average absorption time of fibrin sealant was 21 +/- 1.3 days. CONCLUSIONS: Fibrin sealant is an effective and safe tool to control intraoperative bleeding during pars plana vitrectomy.

Keyword

Fibrin sealant; Pars plana vitrectomy

MeSH Terms

Absorption
Diabetic Retinopathy*
Epiretinal Membrane
Female
Fibrin Tissue Adhesive*
Fibrin*
Hemorrhage*
Humans
Intraoperative Complications
Light Coagulation
Male
Postoperative Complications
Prospective Studies
Retinal Detachment
Traction
Vitrectomy
Fibrin
Fibrin Tissue Adhesive
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