Ann Surg Treat Res.  2014 Sep;87(3):113-117. 10.4174/astr.2014.87.3.113.

The clinical features and optimal treatment of anorectal malignant melanoma

• Nam S
• Kim CW
• Baek SJ
• Hur H
• Min BS
• Baik SH
• Kim NK

• KMID: 1908480
• DOI: http://doi.org/10.4174/astr.2014.87.3.113

Abstract

Anorectal malignant melanoma (AMM) is a very rare and aggressive disease. The purpose of this article is to review the clinical features of AMM, to understand treatment options, and optimal therapy by reviewing pertinent literature. Traditionally an abdominoperineal resection (APR) sacrificing the anal sphincter has been performed for radical resection of cancer, but recently, wide excision of AMM is attempted since quality of life after surgery is an important issue. Some authors reported that there was no difference in five-year survival between the patient who underwent an APR and wide excision. The goal of both APR and wide excision was to improve survival with R0 resection. Adjuvant chemoradiation therapy can be performed to achieve an R0 resection. AMM shows very poor prognosis. At this time, research on AMM is insufficient to suggest a treatment guideline. Thus, treatment options, and a therapeutic method should be selected carefully.

Keyword

Melanoma; Skin neoplasms; Anal neoplasms; Surgery; Wide local excision

MeSH Terms

Anal Canal
Anus Neoplasms
Humans
Melanoma*
Prognosis
Quality of Life
Skin Neoplasms

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