Korean J Gastrointest Endosc.  2001 Jun;22(6):444-448.

Two Cases of Colon Adenocarcinoma Transformed from Colonic Adenoma

Affiliations
  • 1Department of Internal Medicine, Catholic University College of Medicine, Seoul, Korea
  • 2Department of Surgery, Catholic University College of Medicine, Seoul, Korea
  • 3Department of Pathology, Catholic University College of Medicine, Seoul, Korea

Abstract

The prevalence of colorectal cancer is increasing now in Korea and the principal strategy of its management is early detection and surgical resection. Current discussion of the topic of colorectal polyps and cancer is largely based on the concept of the adenoma-carcinoma sequence, which is thought to be the most probable pathogenesis for colorectal cancer. But the case reports about colonic adenocarcinoma arising from adenoma in clinical practice between short interval are rare in Korea. We experienced two cases of colon cancer, which were transformed from small adenoma can not be removed because of patients' refusal, 3 years ago. So we present these cases with a review of relevant literatures.

Keyword

Colon adenocarcinoma; Colonic adenoma; Malignant transformation

MeSH Terms

Adenocarcinoma*
Adenoma*
Colon*
Colonic Neoplasms
Colorectal Neoplasms
Disulfiram
Korea
Polyps
Prevalence
Disulfiram
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