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Disulfiram, a Re-positioned Aldehyde Dehydrogenase Inhibitor, Enhances Radiosensitivity of Human Glioblastoma Cells In Vitro

Koh HK, Seo SY, Kim JH, Kim HJ, Chie EK, Kim SK, Kim IH

PURPOSE: Glioblastoma, the most common brain tumor in adults, has poor prognosis. The purpose of this study was to determine the effect of disulfiram (DSF), an aldehyde dehydrogenase inhibitor, on...
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Anti-tumor activity and mitochondrial stability of disulfiram in HL-60 cells

Disulfiram (DSF) is a member of the dithiocarbamate family that can bind copper. Recent studies have shown that DSF has anti-cancer activities, but the mechanism has not been clarified. Therefore,...
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Epileptic Seizure Due to Disulfiram Treatment

Erensoy H, Sargin AE

Disulfiram has been used for the treatment of alcohol dependence for nearly 65 years and is approved by the Food and Drug Administration. It causes negative reinforcement by accumulating toxic...
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Disulfram Treatment of NUP98-PHF23 AML Is Not Effective In Vivo: Potential Role for Hematopoietic Stem Cells Niche

Park ES, Chung YJ, Aplan PD

BACKGROUND: NUP98 has numerous partner genes of which plant homeodomain (PHD) finger protein 23 (PHF23) fusion with NUP98 (NP23) can be detected by RT-PCR in patients with cytogenetically normal acute...
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Comment on: Disulfiram Induced Psychosis (Mohapatra and Rath, Clin Psychopharmacol Neurosci 2017;15:68-69)

Karamanakos PN, Panteli ES

No abstract available.
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Disulfiram Induced Psychosis

Mohapatra , Rath NR

Disulfiram is the commonly prescribed drug for the treatment of alcohol dependence. It's major metabolite (diethyldithiocarbamate) is an inhibitor of dopamine-betahydroxylase, an enzyme that catalyzes the metabolism of dopamine to...
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Nutritional Supports in Patients with Inflammatory Bowel Disease

Kye BH

Underweight and specific nutrient deficiencies are frequent in adult patients with inflammatory bowel disease (IBD). In addition, a significant number of children with IBD, particularly Crohn's disease (CD) have impaired...
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Multivariate Analysis of Risk Factors Associated With the Nonreversal Ileostomy Following Sphincter-Preserving Surgery for Rectal Cancer

Kim YA, Lee GJ, Park SW, Lee WS, Baek JH

PURPOSE: A loop ileostomy is used to protect an anastomosis after anal sphincter-preserving surgery, especially in patients with low rectal cancer, but little information is available concerning risk factors associated...
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How to Improve Eating Behaviour during Early Childhood

Green RJ, Samy G, Miqdady MS, Salah M, Sleiman R, Abdelrahman HMA, Al Haddad , Reda MM, Lewis H, Ekanem EE, Vandenplas Y

Eating behaviour disorder during early childhood is a common pediatric problem. Many terminologies have been used interchangeably to describe this condition, hindering implementation of therapy and confusing a common problem....
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Factors associated with Problem Drinking in Korean Male Employees for Drinking Motivation, Job Stress, and Drinking Refusal Self-efficacy

Ha Y, Jung MR

PURPOSE: The purpose of this study was to examine relationships between drinking motivation, drinking refusal self-efficacy, job stress and problem drinking, and identify contributing factors on employees' problem drinking. METHODS: A...
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Transfusion free radical antegrade modular pancreaticosplenectomy of metastatic neuroendocrine tumor of the pancreas in Jehovah's Witness patient

Jeon YB, Yun S, Choi D

In a popular sense, Jehovah's Witnesses (JW) have their creeds, one of which is refusal of blood transfusion. Such refusal may impinge on their proper management, especially in critical situations....
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Impact of a "TED-Style" presentation on potential patients' willingness to accept dental implant therapy: a one-group, pre-test posttest study

Ghanem H, Afrashtehfar KI, Abi-Nader , Tamimi F

PURPOSE: A survey was conducted to assess the impact of a TED-like educational session on participants' willingness to accept dental implant therapy. MATERIALS AND METHODS: Volunteers interested in having information about...
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Adaptation Experience among Hemodialysis of Women with End-Stage Renal Disease

Park EJ, Kim YH, Son HM

PURPOSE: This study was a qualitative study to explore and understand the adaptation experiences of hemodialysis among women with End-Stage Renal Disease (ESRD) and to develop a substantive theory using...
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Disulfiram Implantation for the Treatment of Alcoholism: Clinical Experiences from the Plastic Surgeon's Point of View

Sezgin B, Sibar S, Bulam H, Findikcioglu K, Tuncer S, Dogan B

BACKGROUND: Disulfiram implantation is a widely used treatment alternative for alcohol abuse, yet reports on the surgical aspect of disulfiram implantation with respect to patient and drug-related treatment efficacy and...
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Reversible Motor Neuropathy Following Disulfiram Therapy

Park SW, Song SK, Lee JS, Choi JC, Kang JH, Kang SY

  • KMID: 2343541
  • J Korean Neurol Assoc.
  • 2014 Aug;32(3):225-227.
No abstract available.
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Outcome of Local Excision Following Preoperative Chemoradiotherapy for Clinically T2 Distal Rectal Cancer: A Multicenter Retrospective Study (KROG 12-06)

Noh JM, Park W, Kim JS, Koom WS, Kim JH, Choi DH, Park HC

  • KMID: 2167689
  • Cancer Res Treat.
  • 2014 Jul;46(3):243-249.
PURPOSE: The aim of this study was to examine the clinical implications of a pathologically complete response after neoadjuvant chemoradiotherapy (CRT) followed by local excision for patients with cT2 rectal...
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A Study on the Legal Issues and Challenges of Insurance Discrimination Against the Mentally Ill

Shin K

  • KMID: 2343658
  • J Korean Neuropsychiatr Assoc.
  • 2014 Mar;53(2):61-71.
OBJECTIVES: The purpose of this study is to criticize the legal reasoning of refusal to insure or provide coverage to the mentally ill. This study focuses on the antagonistic fundamentals...
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Usefulness of Minimally Invasive Posterior Foraminotomy using Tubular Retractor for Lumbar Spinal Stenosis with Foraminal Stenosis

Shin HK, Choi JY, Jeong HJ, Kim E, Park SJ, Lee SH, Seo DS

STUDY DESIGN: Retrospective study. OBJECTIVES: The aim of this study was to report the usefulness of lumbar posterior foraminotomy and central decompression using tubular retractor with minimally invasive technique. SUMMARY OF LITERATURE...
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Comparison between Natives and Foreigners who Visited an Emergency Center due to Suicidal Attempt

Sung MK, Choi HY, Kang GH, Jang YS, Ohk TG, Kim WJ, Kim YY, Lee YJ, Park SM, Cho Y

PURPOSE: In an effort to determine the characteristics of foreign suicides who visit an emergency center, this study analyzed suicidal attempt between natives and foreigners. METHODS: We conducted a retrospective analysis...
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Successful Treatment of Tracheal Invasion Caused by Thyroid Cancer Using Endotracheal Tube Balloon Inflation under Flexible Bronchoscopic Guidance

Han YH, Jung BH, Kwon JS, Lim J

Tracheal invasion is an uncommon complication of thyroid cancer, but it can cause respiratory failure. A rigid bronchoscope may be used to help relieve airway obstruction, but general anesthesia is...
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