Korean J Gastrointest Endosc.  2005 Apr;30(4):222-225.

Solitary Peutz-Jeghers Polyp of the Colon

Affiliations
  • 1Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea. inos@inha.ac.kr
  • 2Department of Pathology, Inha University College of Medicine, Incheon, Korea.
  • 3Department of Radiology, Inha University College of Medicine, Incheon, Korea.

Abstract

Peutz-Jeghers syndrome is an autosomal-dominant inherited disorder characterized by polyposis of the alimentary tract, the abnormal mucocutaneous pigmentation, and family history of Peutz-Jeghers syndrome. A single Peutz-Jeghers polyp arising in a patient without pigmentation and family history of Peutz-Jeghers syndrome is termed a solitary or isolated hamartomatous polyp of Peutz-Jeghers type. These solitary polyps are found most frequently in the small intestine but also occur in the large bowel and stomach as well. In a healthy 48-year-old man, a single large polyp was found incidentally in the ascending colon during colonoscopy and treated by snare polypectomy. Microscopic exam of the resected specimen revealed the features of hamartomatous polyp of Peutz-Jeghers type. There was no evidence of other polyps on esophagogastroduodenoscopy and small bowel series. We report a patient with solitary Peutz-Jeghers polyp of the colon, who had no stigmata associated with Peutz-Jeghers syndrome.

Keyword

Solitary Peutz-Jeghers polyp; Colon

MeSH Terms

Christianity
Colon*
Colon, Ascending
Colonoscopy
Endoscopy, Digestive System
Humans
Intestine, Small
Middle Aged
Peutz-Jeghers Syndrome
Pigmentation
Polyps*
SNARE Proteins
Stomach
SNARE Proteins
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