Korean J Gastrointest Endosc.  2010 Jul;41(1):36-40.

A Case of Hamartomatous Polyp without Peutz-Jeghers Syndrome Arising from Appendix

• Sohn WS
• Park JS
• Kim JE
• Kim BH
• Yoo SH
• Han EM

Abstract

Peutz-Jeghers syndrome is a familial syndrome consisting of mucocutaneous pigmentation and gastrointestinal polyposis and appears to be inherited as a single pleiotropic autosomal dominant gene with variable and incomplete penetrance. Cases of hamartomatous polyps of the Peutz-Jeghers type without Peutz-Jeghers syndrome have only rarely been reported. Moreover, only one case of a Peutz-Jeghers polyp at the appendix has been reported; it was resected by appendectomy. We report here on a case of a 45 year old man who had a hamartomatous polyp of the Peutz-Jeghers type arising from the appendix. The polyp was successfully removed by endoscopic polypectomy. To our knowledge, this is the first case of a hamartomatous polyp of the Peutz-Jeghers type that originated from the appendix and that was resected endoscopically.

Keyword

Hamartomatous polyp; Peutz-Jeghers type; Appendix; Endoscopic polypectomy

MeSH Terms

Appendectomy
Appendix
Genes, Dominant
Penetrance
Peutz-Jeghers Syndrome
Pigmentation
Polyps