J Korean Soc Biol Psychiatry.  1998 Jun;5(1):102-106.

The Relation of Family History and beta-Endorphin Levels in Alcohol Dependence

• Jeong HY
• Park IJ
• Kwon YJ

Abstract

OBJECTIVES
To evaluated the relation of familial history of alcoholism and plasma level of beta-endorphin, ethanol, beta-endorphin, cortisol and blood glucose were compared in 48 male alcoholics and 29 normal controls.
METHODS
Subjects are divided into two groups by family history of alcoholism. Blood samples were obtained before and after 0.75mg/kg of ethanol consumption a 7th admission day.
RESULTS
1) The ratio of family history positive to negative of the patient group was 2 to 1. 2) The age at admission of positive family history group was younger than negative groups. 3) There was no significant difference in change of plasma ethanol level among three groups. 4) There was no significant difference in change of plasma beta-endorphin level among three group. 5) There was no significant difference in change of plasma cortisol level among three groups. 6) There was no significant difference in change of fasting blood sugar level between two patients groups.

MeSH Terms

Alcoholics
Alcoholism*
beta-Endorphin*
Blood Glucose
Ethanol
Fasting
Humans
Hydrocortisone
Male
Plasma
Blood Glucose
Ethanol
Hydrocortisone
beta-Endorphin