Korean J Med.  2013 Mar;84(3):395-399. 10.3904/kjm.2013.84.3.395.

Two Cases of Refractory Pseudomembranous Colitis that Healed Following Fecal Microbiota Transplantation

Affiliations
  • 1Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. viper@catholic.ac.kr

Abstract

The incidence, recurrence, and mortality of Clostridium difficile infection are increasing and the standard therapy is oral metronidazole or vancomycin. Since treatment failure with standard therapy is increasing, an alternative therapy is needed. Fecal microbiota transplantation is one effective method in patients with refractory or recurrent C. difficile infection, including pseudomembranous colitis. Here, we report two cases of refractory pseudomembranous colitis treated with fecal microbiota transplantation.

Keyword

C. difficile infection; Pseudomembranous colitis; Fecal microbiota transplantation

MeSH Terms

Clostridium difficile
Enterocolitis, Pseudomembranous
Humans
Incidence
Metagenome
Metronidazole
Recurrence
Transplants
Treatment Failure
Vancomycin
Metronidazole
Vancomycin
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