- Imbalance of Gut Streptococcus, Clostridium, and Akkermansia Determines the Natural Course of Atopic Dermatitis in Infant
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Park YM, Lee SY, Kang MJ, Kim BS, Lee MJ, Jung SS, Yoon JS, Cho HJ, Lee E, Yang SI, Seo JH, Kim HB, Suh DI, Shin YH, Kim KW, Ahn K, Hong SJ
- KMID: 2468465
- Allergy Asthma Immunol Res.
- 2020 Mar;12(2):322-337.
- doi: 10.4168/aair.2020.12.2.322
PURPOSE: The roles of gut microbiota on the natural course of atopic dermatitis (AD) are not yet fully understood. We investigated whether the composition and function of gut microbiota and... -
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- Oral Metagenomic Analysis Techniques
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Chung SK
- KMID: 2451786
- J Dent Hyg Sci.
- 2019 Jun;19(2):86-95.
- doi: 10.17135/jdhs.2019.19.2.86
The modern era of microbial genome analysis began in earnest in the 2000s with the generalization of metagenomics and gene sequencing techniques. Studying complex microbial community such as oral cavity... -
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- Oral and Human Microbiome Research
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Chung SK
- KMID: 2451785
- J Dent Hyg Sci.
- 2019 Jun;19(2):77-85.
- doi: 10.17135/jdhs.2019.19.2.77
In the past gut microbiome has been the main focus of microbiome research. Studies about the microbiome inside oral cavities and other organs are underway. Studies about the relationship between... -
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- Statistical Analysis of Metagenomics Data
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Calle ML
- KMID: 2447796
- Genomics Inform.
- 2019 Mar;17(1):e6.
- doi: 10.5808/GI.2019.17.1.e6
Understanding the role of the microbiome in human health and how it can be modulated is becoming increasingly relevant for preventive medicine and for the medical management of chronic diseases.... -
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- Comparison of differences in microbial compositions between negative controls and subject samples with varying analysis configurations
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Kim H, Lee SP, Kang SM, Kang SY, Jung S, Lee SM
- KMID: 2421216
- Allergy Asthma Respir Dis.
- 2018 Sep;6(5):255-262.
- doi: 10.4168/aard.2018.6.5.255
PURPOSE: Identifying microbial communities with 16S ribosomal RNA (rRNA) gene sequencing is a popular approach in microbiome studies, and various software tools and data resources have been developed for microbial... -
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- Human Resistome Study with Metagenomic Sequencing Data
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Shin JH, Rho M
- KMID: 2431302
- Hanyang Med Rev.
- 2018 Jun;38(2):73-79.
- doi: 10.7599/hmr.2018.38.2.73
With the introduction of synthetic antibiotics, many lives including humans and animals have been saved against bacterial infection. An increasing level of antibiotics use, however, raises serious problems of multi-drug... -
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- Comparative Analysis of Ileal and Cecal Microbiota in Aged Rats
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Lee SM, Kim N, Park JH, Nam RH, Yoon K, Lee DH
- KMID: 2417369
- J Cancer Prev.
- 2018 Jun;23(2):70-76.
- doi: 10.15430/JCP.2018.23.2.70
BACKGROUND: Gut microbiota contributes to intestinal and immune homeostasis through host-microbiota interactions. Distribution of the gut microbiota differs according to the location in the gastrointestinal tract. Although the microbiota properties... -
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- Metagenome Analysis of Bodily Microbiota in a Mouse Model of Alzheimer Disease Using Bacteria-derived Membrane Vesicles in Blood
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Park JY, Choi J, Lee Y, Lee JE, Lee EH, Kwon HJ, Yang J, Jeong BR, Kim YK, Han PL
- KMID: 2398425
- Exp Neurobiol.
- 2017 Dec;26(6):369-379.
- doi: 10.5607/en.2017.26.6.369
Emerging evidence has suggested that the gut microbiota contribute to brain dysfunction, including pathological symptoms of Alzheimer disease (AD). Microbiota secrete membrane vesicles, also called extracellular vesicles (EVs), which contain... -
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- Rapid Assessment of Microbiota Changes in Individuals with Autism Spectrum Disorder Using Bacteria-derived Membrane Vesicles in Urine
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Lee Y, Park JY, Lee EH, Yang J, Jeong BR, Kim YK, Seoh JY, Lee S, Han PL, Kim EJ
- KMID: 2398435
- Exp Neurobiol.
- 2017 Oct;26(5):307-317.
- doi: 10.5607/en.2017.26.5.307
Individuals with autism spectrum disorder (ASD) have altered gut microbiota, which appears to regulate ASD symptoms via gut microbiota-brain interactions. Rapid assessment of gut microbiota profiles in ASD individuals in... -
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- Inflammasomes in antiviral immunity: clues for influenza vaccine development
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Yamazaki T, Ichinohe T
- KMID: 2049091
- Clin Exp Vaccine Res.
- 2014 Jan;3(1):5-11.
- doi: 10.7774/cevr.2014.3.1.5
Inflammasomes are cytosolic multiprotein complexes that sense microbial motifs or cellular stress and stimulate caspase-1-dependent cytokine secretion and cell death. Recently, it has become increasingly evident that both DNA and... -
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- Regulation of Intestinal Homeostasis by Innate Immune Cells
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Kayama H, Nishimura , Takeda K
- KMID: 2150782
- Immune Netw.
- 2013 Dec;13(6):227-234.
- doi: 10.4110/in.2013.13.6.227
The intestinal immune system has an ability to distinguish between the microbiota and pathogenic bacteria, and then activate pro-inflammatory pathways against pathogens for host defense while remaining unresponsive to the... -
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- Analysis of Oropharyngeal Microbiota between the Patients with Bronchial Asthma and the Non-Asthmatic Persons
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Dang HT, Kim SA, Park HK, Shin JW, Park SG, Kim W
- KMID: 1501995
- J Bacteriol Virol.
- 2013 Dec;43(4):270-278.
- doi: 10.4167/jbv.2013.43.4.270
Bronchial asthma can be triggered by microbial agents in the oropharynx. This study was designed to identify the differences in microbiota of oropharynx of bronchial asthmatic patients in contrast to... -
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- Abdominal Bloating: Pathophysiology and Treatment
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Seo AY, Kim N, Oh DH
- KMID: 2325764
- J Neurogastroenterol Motil.
- 2013 Oct;19(4):433-453.
Abdominal bloating is a very common and troublesome symptom of all ages, but it has not been fully understood to date. Bloating is usually associated with functional gastrointestinal disorders or... -
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- Bioprospecting Potential of the Soil Metagenome: Novel Enzymes and Bioactivities
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Lee MH, Lee SW
- KMID: 2009103
- Genomics Inform.
- 2013 Sep;11(3):114-120.
- doi: 10.5808/GI.2013.11.3.114
The microbial diversity in soil ecosystems is higher than in any other microbial ecosystem. The majority of soil microorganisms has not been characterized, because the dominant members have not been... -
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- Clinical efficacy and mechanism of probiotics in allergic diseases
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Kim HJ, Kim HY, Lee SY, Seo JH, Lee E, Hong SJ
- KMID: 1493117
- Korean J Pediatr.
- 2013 Sep;56(9):369-376.
- doi: 10.3345/kjp.2013.56.9.369
A complex interplay between genetic and environmental factors partially contributes to the development of allergic diseases by affecting development during prenatal and early life. To explain the dramatic increase in... -
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- Role of Intestinal Microbiota in Inflammatory Bowel Diseases
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Eun CS
- KMID: 1974779
- Intest Res.
- 2013 Jul;11(3):161-168.
- doi: 10.5217/ir.2013.11.3.161
A vast number of micro-organisms within the human gut play a crucial role in maintaining human health. Intestinal microbiota maintains the intestinal homeostasis and function by mutually interacting with the... -
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- Current Status and Future Promise of the Human Microbiome
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Kim BS, Jeon YS, Chun J
- KMID: 2315410
- Pediatr Gastroenterol Hepatol Nutr.
- 2013 Jun;16(2):71-79.
The human-associated microbiota is diverse, varies between individuals and body sites, and is important in human health. Microbes in human body play an essential role in immunity, health, and disease.... -
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- Epigenetic biomarkers: a step forward for understanding periodontitis
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Lindroth A, Park YJ
- KMID: 1798484
- J Periodontal Implant Sci.
- 2013 Jun;43(3):111-120.
- doi: 10.5051/jpis.2013.43.3.111
Periodontitis is a common oral disease that is characterized by infection and inflammation of the tooth supporting tissues. While its incidence is highly associated with outgrowth of the pathogenic microbiome,... -
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- Two Cases of Refractory Pseudomembranous Colitis that Healed Following Fecal Microbiota Transplantation
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Gweon TG, Choi MG, Lee SK, Ha JH, Kim EY, Go BS, Kim SW
- KMID: 1833849
- Korean J Med.
- 2013 Mar;84(3):395-399.
- doi: 10.3904/kjm.2013.84.3.395
The incidence, recurrence, and mortality of Clostridium difficile infection are increasing and the standard therapy is oral metronidazole or vancomycin. Since treatment failure with standard therapy is increasing, an alternative... -
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- Molecular Methods for Studying the Human Microbiota
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Choi YH, Chung J, Na HS
- KMID: 1782705
- J Bacteriol Virol.
- 2013 Mar;43(1):67-72.
- doi: 10.4167/jbv.2013.43.1.67
Vast array of microbes colonize to each anatomical environment of human body. Culture based methods are important in investigating the microbial structure, but they are extremely biased in their evaluation... -
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