Korean J Hematol.  2001 May;36(2):162-166.

A Case with Plasma Cell Leukemia and Anaplastic Large T cell Lymphoma

Affiliations
  • 1Department of Clinical Pathology, University of Ulsan College of Medicine and Asan Medical center, Seoul, Korea.
  • 2Department of Pathology, University of Ulsan College of Medicine and Asan Medical center, Seoul, Korea.
  • 3Department of Hemato-oncology, University of Ulsan College of Medicine and Asan Medical center, Seoul, Korea.

Abstract

The association of B-cell and T-cell disorders is rare. We report a case with coexisting plasma cell leukemia and anaplastic large T cell lymphoma. It is believed to be the first case reported in the literature. A 49-year man was admitted to the hospital because of indigestion. On the gastrofibroscopic examination, a huge, ulcerofungating mass was detected in the stomach, and Ki-1 positive anaplastic large T-cell lymphoma was diagnosed on the biopsy. On the peripheral blood smear and bone marrow study performed as a part of the staging work-up, plasma cell leukemia was diagnosed. The protein electrophoresis and immunofixation of serum and urine revealed IgG, lamda type monoclonal gammopathy. But in the pleural effusion, the involvement of anaplastic large T-cell lymphoma was noted.

Keyword

Plasma cell leukemia; Anaplastic large T-cell lymphoma

MeSH Terms

B-Lymphocytes
Biopsy
Bone Marrow
Dyspepsia
Electrophoresis
Immunoglobulin G
Leukemia, Plasma Cell*
Lymphoma, T-Cell*
Paraproteinemias
Plasma Cells*
Plasma*
Pleural Effusion
Stomach
T-Lymphocytes
Immunoglobulin G
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