Korean J Anesthesiol.  2011 Jan;60(1):36-40. 10.4097/kjae.2011.60.1.36.

Post-operative nausea and vomiting after gynecologic laparoscopic surgery: comparison between propofol and sevoflurane

• Shinn HK
• Lee MH
• Moon SY
• Hwang SI
• Lee CS
• Lim HK
• Song JH

• KMID: 1827996
• DOI: http://doi.org/10.4097/kjae.2011.60.1.36

Abstract

BACKGROUND
We compared the incidence and degree of post-operative nausea and vomiting (PONV) in patients who received general anesthesia with propofol or sevoflurane using the Rhodes index of nausea, vomiting, and retching (RINVR) to assess the degree of PONV quantitatively and objectively during the post-anesthetic period.
METHODS
We performed a prospective study involving 38 patients who underwent gynecologic laparoscopic surgery in our hospital between September 2008 and August 2009. Nineteen patients were anesthetized with propofol during the entire anesthetic period and the other 19 patients received 2.0 mg/kg of propofol intravenously, followed by sevoflurane inhalation. Three patients who were anesthetized with sevoflurane were excluded from the analysis because they were omitted during the survey. We studied the patients who had PONV and RINVR scores 1, 6, and 24 hours post-operatively.
RESULTS
The propofol group had a statistically lower incidence of PONV and lower RINVR scores in the following subclasses within 1 hour of surgery: symptom occurrence; symptom distress; and symptom experience.
CONCLUSIONS
Propofol at induction and during maintenance of anesthesia can be used to prevent PONV within 1 hour post-operatively in patients undergoing gynecologic laparoscopic surgery.

Keyword

Laparoscopic surgery; Post-operative nausea and vomiting; Propofol; Sevoflurane

MeSH Terms

Anesthesia
Anesthesia, General
Humans
Incidence
Inhalation
Laparoscopy
Methyl Ethers
Nausea
Postoperative Nausea and Vomiting
Propofol
Prospective Studies
Vomiting
Methyl Ethers
Propofol