Yonsei Med J.  2011 Mar;52(2):362-364. 10.3349/ymj.2011.52.2.362.

Prostate Cancer with Solitary Metastases to the Bilateral Testis

• Kim SO
• Choi YD
• Jung SI
• Oh KJ
• Im CM
• Kang TW
• Kwon D
• Park K
• Ryu SB

• KMID: 1779677
• DOI: http://doi.org/10.3349/ymj.2011.52.2.362

Abstract

We present the case of an 81-year-old patient with testicular metastasis from prostate carcinoma. After the initial diagnosis of prostate cancer, he had an 8-year course of hormonal therapy and showed no clinical evidence of metastasis to other organs. Asymptomatic metastasis of prostate carcinoma to the testis is a rare clinical condition. We diagnosed his condition, based on histopathology following a subcapsular orchiectomy and transurethral resection of the prostate.

Keyword

Testis; prostatic carcinoma; metastasis

MeSH Terms

Adenocarcinoma/*pathology/surgery
Aged, 80 and over
Humans
Male
Neoplasm Metastasis
Orchiectomy
Prostatic Neoplasms/*pathology/surgery
Testicular Neoplasms/*secondary/surgery
Transurethral Resection of Prostate

Figure

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  Fig. 1 Neoplasm infiltrating the hole testicular tissue (arrow) with adenocarcinoma. The testis shows an invasion by prostatic adenocarcinoma (×40) and resected prostate tissue (×150)(H&E).

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  Fig. 2 Tumor cells show a strong positive stain for prostate specific antigen (PSA) (A) and p504s (B) (×200).

Reference

1. Dutt N, Bates AW, Baithun SI. Secondary neoplasms of the male genital tract with different patterns of involvement in adults and children. Histopathology. 2000. 37:323–331.

2. Patel SR, Richardson RL, Kvols L. Metastatic cancer to the testes: a report of 20 cases and review of the literature. J Urol. 1989. 142:1003–1005.

3. Johansson JE, Lannes P. Metastases to the spermatic cord, epididymis and testicles from carcinoma of the prostate--five cases. Scand J Urol Nephrol. 1983. 17:249–251.

4. Pienkos EJ, Jablokow VR. Secondary testicular tumors. Cancer. 1972. 30:481–485.

5. Richie JP, Steele GS. Walsh PC, Retik AB, Vaughan ED, Wein AJ, editors. Neoplasms of the testis. Campbell's Urology. 2002. 8th ed. Philadelphia: W.B. Saunders;2876–2919.