Yonsei Med J.  2004 Dec;45(6):1043-1048. 10.3349/ymj.2004.45.6.1043.

IgA Nephropathy in Renal Allografts-Recurrence and Graft Dysfunction

• Jeong HJ
• Huh KH
• Kim YS
• Kim SI

• KMID: 1726166
• DOI: http://doi.org/10.3349/ymj.2004.45.6.1043

Abstract

With time after transplantation, the recurrence of IgA nephropathy (IgAN) becomes a relevant cause of graft dysfunction and failure. However, only limited information has been published regarding the related clinical and histological features. In this article, we review studies on recurrent IgAN in the English literature and describe our own clinical experience. The clinical and histological features related to recurrence are still indeterminate, but features associated with graft dysfunction include proteinuria, glomerulosclerosis, mesangial proliferation, glomerular crescents and interstitial fibrosis.

Keyword

IgA nephropathy; renal transplantation; recurrence; histology; proteinuria

MeSH Terms

Glomerulonephritis, IGA/*physiopathology/*surgery
Humans
Kidney/*physiopathology
*Kidney Transplantation
Recurrence
Research Support, Non-U.S. Gov't
Transplantation, Homologous