Korean J Gastroenterol.  2012 Jul;60(1):13-18. 10.4166/kjg.2012.60.1.13.

Incidence and Risk Factors of Irritable Bowel Syndrome in Community Subjects with Culture-proven Bacterial Gastroenteritis

• Koh SJ
• Lee DH
• Lee SH
• Park YS
• Hwang JH
• Kim JW
• Jeong SH
• Kim N
• Im JP
• Kim JS
• Jung HC

• KMID: 1718461
• DOI: http://doi.org/10.4166/kjg.2012.60.1.13

Abstract

BACKGROUND/AIMS
The aim of this study was to investigate the incidence and risk factors of irritable bowel syndrome (IBS) in community subjects with culture-proven bacterial gastroenteritis.
METHODS
This was a prospective, community-based, cohort study, which followed patients with a recent history of culture-proven bacterial gastroenteritis. IBS was diagnosed with the use of the Rome II criteria at 3 and 6 months after bacterial dysentery.
RESULTS
Sixty five cases were included and completed the 6 month follow-up. Thirty four cases (52.3%) were female. Salmonella was the pathogen most frequently identified and seen in 41 patients (63.1%). The cumulative incidence of IBS among patients with microbiologically proven bacterial gastroenteritis within a community was 9.2% and 12.3% at 3 and 6 months of follow-up, respectively. The duration of initial diarrhea (> or =7 days) was associated with an increased risk for the development of IBS (aOR, 14.50 [95% CI, 1.38-152.72]; p=0.022).
CONCLUSIONS
Our study suggests that the incidence of IBS among patients with culture-proven bacterial gastroenteritis within a community is similar to that reported among Western populations. A large, prospective study is encouraged to confirm our results and to evaluate the influence of the microbial species on the epidemiology of IBS in Asian populations.

Keyword

Irritable bowel syndrome; Bacterial gastroenteritis; Diarrhea

MeSH Terms

Adolescent
Adult
Aged
Cohort Studies
Diarrhea/complications
Dysentery/complications
Female
Follow-Up Studies
Gastroenteritis/*complications/epidemiology/microbiology
Humans
Incidence
Irritable Bowel Syndrome/*diagnosis/epidemiology/etiology
Male
Middle Aged
Odds Ratio
Prospective Studies
Risk Factors
Salmonella/isolation & purification
Shigella/isolation & purification
Young Adult

Figure

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  Fig. 1 The development of irritable bowel syndrome (IBS) after bacterial dysentery during the 6-month of follow-up.

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