Korean J Dermatol.  1993 Jun;31(3):449-455.

A case of leukemia cutis

• Hong SH
• Seo SJ
• Hong CK
• Lee SJ
• Song KY
• Ro BI

Abstract

Leukemia cutis are clinically divided into the specific and nonspecific types. The former demon strates a malignant cell infiltrate on histopathologic examination. We report a case of leukemia cutis in a 29-year old female which developed specific cutanous manifestations previous to peripheral blood abnormalities, She had suffered from several discrete, bean to walnut sized, tender, erythematous patches and nodules on the trunk for 3 months and these gradually spread to the right cheek and upper arm. Atypical lymphocytes and incesassed lymphoblasts were notifced on a peripheral blood smear and bone marrow aspiration. A bone marrow biopsy revealed compact marrow finding, and increased celluarity. The histopathlogic findings showed diffuse dermal and subcutaneous infiltration of atypical lymphocytes. An immunohistochemical study with kappa, lamda, and leukocyte common antigen(LCA) revealed lymphoid malignancy, T-cell type. We treated her with various combined chemotherapy for 2 year, but her skin lesions were not inproved.

MeSH Terms

Adult
Arm
Biopsy
Bone Marrow
Cheek
Drug Therapy
Female
Humans
Juglans
Leukemia*
Leukocytes
Lymphocytes
Skin
T-Lymphocytes