- Similar transplant outcomes between haploidentical and unrelated donors after reduced-intensity conditioning with busulfan, fludarabine, and anti-thymocyte globulin in patients with acute leukemia or myelodysplastic syndrome
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Choi M, Heo JY, Shin DY, Lee JY, Koh Y, Hong J, Kim I, Yoon SS, Lee JO, Bang SM
- KMID: 2472005
- Blood Res.
- 2020 Mar;55(1):27-34.
- doi: 10.5045/br.2020.55.1.27
BACKGROUND: Although T-cell-replete hematopoietic cell transplantation (HCT) from haploidentical donors (HIDs) using anti-thymocyte globulin (ATG) has shown promising outcomes, previous studies often adopted heterogenous graft sources and conditioning. METHODS: We retrospectively... -
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- A general view of CD33⺠leukemic stem cells and CAR-T cells as interesting targets in acute myeloblatsic leukemia therapy
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Fathi E, Farahzadi , Sheervalilou R, Sanaat Z, Vietor I
- KMID: 2472003
- Blood Res.
- 2020 Mar;55(1):10-16.
- doi: 10.5045/br.2020.55.1.10
Acute myeloblastic leukemia (AML) is the most frequent acute leukemia in adulthood with very poor overall survival rates. In the past few decades, significant progresses had led to the findings... -
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- Acute Leukemia Relapse Presenting as Recurrent Involvement of the Optic Nerve
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Lee SY, Yoon JH, Chung SA
- KMID: 2471776
- J Korean Ophthalmol Soc.
- 2020 Mar;61(3):319-324.
- doi: 10.3341/jkos.2020.61.3.319
PURPOSE: To report two cases with recurrent involvement of the optic nerve as the initial sign of acute leukemic relapse. CASE SUMMARY: An 8-year-old male with acute lymphoblastic leukemia on the... -
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- A Case of Donor Cell Leukemia after Allogenic Peripheral Blood Stem Cell Transplantation for Acute Promyelocytic Leukemia with PML-RARA
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Shin WY, Bang HI, Kim J, Kim KH, Won JH, Park R
- KMID: 2466771
- Lab Med Online.
- 2020 Jan;10(1):88-91.
- doi: 10.3343/lmo.2020.10.1.88
Donor cell leukemia (DCL), a rare but fatal complication arising from allogenic stem cell transplantation, is a complex disease associated with multiple pathophysiological processes. Specific diagnosis of DCL distinct from... -
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- Leukostasis by hyperleukocytic childhood acute leukemia: pathophysiology, clinical presentation, and emergency care
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Nam KL, Baek GY, Jeon IS
- KMID: 2469716
- Pediatr Emerg Med J.
- 2019 Dec;6(2):35-41.
- doi: 10.22470/pemj.2019.00150
Hyperleukocytosis (HL), defined by a peripheral white blood cell (WBC) count exceeding 100,000/mm³, is occasionally observed in childhood acute leukemia. The increased viscosity in the micro-circulation by HL and the... -
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- Differential impact of anti-thymocyte globulin dosing by disease risk index in alternative donor peripheral blood stem cell transplantation in patients with acute leukemia or myelodysplastic syndrome after reduced intensity conditioning
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Choi M, Shin DY, Lee JY, Kim I, Yoon SS, Bang SM
- KMID: 2466598
- Blood Res.
- 2019 Dec;54(4):290-295.
- doi: 10.5045/br.2019.54.4.290
No abstract available. -
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- Leukemia Cutis in Chronic Neutrophilic Leukemia Associated with Colony Stimulating Factor 3 Receptor Mutation: Clinical Severity Paralleled with Hematologic Abnormality
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Kwon O, Park J, Chung H, Park KD
- KMID: 2461992
- Ann Dermatol.
- 2019 Dec;31(6):673-677.
- doi: 10.5021/ad.2019.31.6.673
Cutaneous lesions of leukemia cutis (LC) by chronic neutrophilic leukemia (CNL) have been merely reported due to the rare occurrences of CNL. Furthermore cutaneous lesions in relation to clinical severity... -
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- microRNA-146a Promotes Growth of Acute Leukemia Cells by Downregulating Ciliary Neurotrophic Factor Receptor and Activating JAK2/STAT3 Signaling
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Wang L, Zhang H, Lei D
- KMID: 2459145
- Yonsei Med J.
- 2019 Oct;60(10):924-934.
- doi: 10.3349/ymj.2019.60.10.924
PURPOSE: Acute leukemia (AL) is classified as acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). This study aimed to investigate the effect of miR-146a on childhood AL and its... -
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- Stress Induced Cardiomyopathy Requiring Ventricular Assist Device Support in an 8-Year-Old Girl with Acute Leukemia
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Park SH, Song MK, Kim GB, Bae EJ, Hong KT, Kwak JG
- KMID: 2458576
- Chonnam Med J.
- 2019 Sep;55(3):179-180.
- doi: 10.4068/cmj.2019.55.3.179
No abstract available. -
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- Concurrent Leukemia Cutis and Sweet Syndrome in a Patient with Acute Myeloid Leukemia
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Kim TL, Jang JW, Shin DS, Kang HS, Seo HM, Kim JS
- KMID: 2454384
- Korean J Dermatol.
- 2019 Jul;57(6):350-352.
No abstract available. -
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- Usefulness of Chromosomal Microarray in Hematologic Malignancies: A Case of Aggressive NK-cell Leukemia with 1q Abnormality
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Chung YN, Kim HN, Lee SR, Sung HJ, Nam MH
- KMID: 2450847
- Lab Med Online.
- 2019 Jul;9(3):189-193.
- doi: 10.3343/lmo.2019.9.3.189
A variety of clonal cytogenetic abnormalities have been reported in aggressive natural killer (NK)-cell lymphoma and leukemia. Recent chromosomal microarray studies have shown both gain and loss of 1q and... -
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- Large Unstained Cell, Blast Suspect and Delta Neutrophil Index ll Analyzed with Automated Hematology Analyzer as Parameters for the Prediction of Acute Leukemia Relapse
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Hwang N, Kim YK, Suh JS
- KMID: 2450837
- Lab Med Online.
- 2019 Jul;9(3):126-132.
- doi: 10.3343/lmo.2019.9.3.126
BACKGROUND: Here we investigated the clinical utilities of blast suspect, large unstained cell (LUC), delta neutrophil index ll (DN ll), and delta neutrophil index l (DN l), analyzed in peripheral... -
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- The Incidence and Immunophenotypic and Genetic Features of JL1 Expressing Cells and the Therapeutic Potential of an Anti-JL1 Antibody in De Novo Pediatric Acute Leukemias
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Park SH, You E, Park CJ, Jang S, Cho YU, Yoon CH, Koh KN, Im HJ, Seo JJ
- KMID: 2438882
- Ann Lab Med.
- 2019 Jul;39(4):358-366.
- doi: 10.3343/alm.2019.39.4.358
BACKGROUND: JL1 is a newly identified CD43 epitope that specifically recognizes leukemic cells. We analyzed the incidence of JL1 expression and compared the clinical, immunophenotypic, and genetic characteristics of de... -
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- Biphenotypic acute leukemia or acute leukemia of ambiguous lineage in childhood: clinical characteristics and outcome
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Lee HG, Baek HJ, Kim HS, Park SM, Hwang TJ, Kook H
- KMID: 2451058
- Blood Res.
- 2019 Mar;54(1):63-73.
- doi: 10.5045/br.2019.54.1.63
BACKGROUND: Acute leukemia (AL), not clearly assigned to myeloid, B-lymphoid, or T-lymphoid lineage, is classified as either biphenotypic acute leukemia (BAL) based on the European Group for Immunological Classification of... -
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- Induction of Apoptosis Scutellaria baicalensis Georgi Root Extract by Inactivation of the Phosphatidyl Inositol 3-kinase/Akt Signaling Pathway in Human Leukemia U937 Cells
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Choi EO, Hwang HJ, Choi YH
- KMID: 2447436
- J Cancer Prev.
- 2019 Mar;24(1):11-19.
- doi: 10.15430/JCP.2019.24.1.11
BACKGROUND: The roots of Scutellaria baicalensis Georgi (Labiatae) have been widely used in traditional medicine for treatment of various diseases. In this study, we investigated the effects of ethanol extracts... -
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- Predictive Role of Circulating Immune Cell Subtypes Early after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Leukemia
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Kim TW, Park SS, Lim JY, Min GJ, Park S, Jeon YW, Yahng SA, Shin SH, Lee SE, Yoon JH, Cho BS, Eom KS, Lee S, Kim HJ, Min CK
- KMID: 2447226
- Int J Stem Cells.
- 2019 Mar;12(1):73-83.
- doi: 10.15283/ijsc18094
BACKGROUND AND OBJECTIVES: Cells of innate immunity normally recover in the first weeks to months after allogenenic hematopoietic stem cell transplantation (allo-HSCT). Their relevance in terms of graft-versus-host disease (GVHD)... -
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- Silencing the PIK3CA Gene Enhances the Sensitivity of Childhood Leukemia Cells to Chemotherapy Drugs by Suppressing the Phosphorylation of Akt
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Liang X, Xin X, Qi D, Fu C, Ding M
- KMID: 2431635
- Yonsei Med J.
- 2019 Feb;60(2):182-190.
- doi: 10.3349/ymj.2019.60.2.182
PURPOSE: This study aimed to investigate the effects of PIK3CA on the sensitivity of acute B lymphocytic leukemia cells (Nalm-6 cells) to chemotherapy drugs. MATERIALS AND METHODS: Children's normal B lymphocytes... -
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- Posttraumatic Growth of Adolescents with Childhood Leukemia and their Parents
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Hong S, Park HR, Choi SH
- KMID: 2433553
- Child Health Nurs Res.
- 2019 Jan;25(1):9-16.
- doi: 10.4094/chnr.2019.25.1.9
PURPOSE: Childhood leukemia is a serious trauma affecting both adolescents and their parents, who experience painful process. However, adolescents with leukemia and their parents also experience positive changes, which is... -
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- Diagnosis of Acute Leukemia from Oral Manifestation
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Kang MH, On D, Kim JW, Ryu J
- KMID: 2437345
- J Korean Dent Sci.
- 2018 Dec;11(2):82-85.
- doi: 10.5856/JKDS.2018.11.2.82
Leukemia is a hematological malignant disease with various clinical symptoms. Due to the fatal nature of the disease, early detection is important. Oral manifestations include ulcers and gingival enlargement with... -
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- Predictors of the Posttraumatic Growth in Parents of Children with Leukemia
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Hong S, Park HR, Choi SH
- KMID: 2431005
- Asian Oncol Nurs.
- 2018 Dec;18(4):224-231.
- doi: 10.5388/aon.2018.18.4.224
PURPOSE: Parents caring for children with leukemia experience a tremendous challenge to get positive results in overcoming traumatic events with their children. The purpose of this study was to identify... -
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