Korean J Dermatol.  1980 Aug;18(4):313-320.

Bowen's Disease and Internal Malignacy

Abstract

It is well known that Bowen's.disease, a precancerous dermatosis can be associated with internal malignancy. We report 2 cases of Bowen's disease of probable arsenic origin associated with. internal malignancies. Case one, a 55 year-old man, who had the past history of arsenic intake and herb medication for the treatment of suspicious leprosy, had Bowen's disease and arsenical keratosis on his palms and soles with bronchogenic and stomach carcinoma. The other case, a 65 year-old man, who had history of intake of arsenic and herb medicine for epilepsy, had Bowen's disease and squamous cell carcinoma of the skin with stomach cancer. We suggest that in these 2 cases, the ingestion of organic arsenics might be the causative factor for the internal malignancy.


MeSH Terms

Aged
Arsenic
Bowen's Disease*
Carcinoma, Squamous Cell
Eating
Epilepsy
Humans
Keratosis
Leprosy
Middle Aged
Skin
Skin Diseases
Stomach
Stomach Neoplasms
Arsenic
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