Korean Circ J.  1985 Dec;15(4):639-644. 10.4070/kcj.1985.15.4.639.

Antihypertensive Effect of Low-Dose Clonidine Monotherapy

• Seo JD
• Kim JS
• Lee CK
• Ryoo UH
• Park OK
• Suh SK

• KMID: 1677317
• DOI: http://doi.org/10.4070/kcj.1985.15.4.639

Abstract

The antihypertensive effect of clonidine was evaluated in 129 patients with essential hypertension of mild to moderate severity with a dosage of one tablet(0.075mg) a day for 71 patients of Group I and two tablets a day for 58 patients of Group II. The results were as follows : 1) Of 71 patients of Group I, 34 patients(47.9%)showed good antihypertensive effect(greater than 15 mmHg drop in mean diastolic pressure) and 11 patients(15.5%) showed fair effect(10-14 mmHg drop in mean diastolic pressure). 2) Of 58 patients of Group II, 39 patients(67.2%) showed good effect and 7 patients(12.1%) showed fair effect. 3) The side effect observed was transient and tolerable dry mouth, which developed in 5.6% of Group I patients and 13.6% of Group II patients.

MeSH Terms

Clonidine*
Humans
Hypertension
Mouth
Tablets
Clonidine
Tablets