J Korean Neurol Assoc.  2003 Feb;21(1):109-110.

A Case of Time-locked Periodic Myoclonus in Pontine Infarction

Affiliations
  • 1Department of Neurology, Seoul Municipal Boramae Hospital, College of Medicine, Seoul National University, 395 Shindaebang 2-dong, Dongjak-gu, Seoul, 156-707, Korea. lys@brm.co.kr

Abstract

Post-stroke involuntary movements are often noted but time-locked myoclonus has not yet been reported. A 53-year-old man was admitted with mild left side weakness and ataxia. He also had involuntary jerky movement of limbs from the onset, which occurred exactly at 11: 00 PM everyday. Symptoms lasted for 30 minutes and were relieved by clonazepam. Brain MRI showed high signal lesion on right pontine tegmentum. We suggest that this time-locked phenomenon may be related with reticular structures containing the so called, "human biological clock".

Keyword

Myoclonus; Time-locked phenomenon; Stroke

MeSH Terms

Ataxia
Brain
Clonazepam
Dyskinesias
Extremities
Humans
Infarction*
Magnetic Resonance Imaging
Middle Aged
Myoclonus*
Stroke
Clonazepam
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