Korean J Gastrointest Endosc.  2003 Sep;27(3):153-157.

A Case of Adenocarcinoma Arising in Hyperplastic Polyp in the Stomach

Affiliations
  • 1Department of Internal Medicine, Soon Chun Hyang University College of Medicine, Seoul, Korea. schidr@hosp.sch.ac.kr
  • 2Department of Clinical Pathology, Soon Chun Hyang University College of Medicine, Seoul, Korea.
  • 3Institute for Digestive Research, Soon Chun Hyang University College of Medicine, Seoul, Korea.

Abstract

Epithelial gastric polyps can be categorized as hyperplastic or adenomatous polyps. Hyperplastic polyps are predominant, comprising 75 to 90% of gastric polyps. It has been generally accepted that adenomatous gastric polyps exhibit malignant change. However, potential of malignant transformation of hyperplastic gastric polyps was originally denied and have been rarely reported, the incidence varying from 1.5 to 2.1%. The size and the associated dysplasia of polyps seem to be important in transformation to gastric carcinoma. Most of the reported cases of hyperplastic gastric polyps with transformation to adenocarcinoma were histopathologically well differentiated. We report a rare case of moderately differentiated adenocarcinoma arising in a hyperplastic polyp on the greater curvature of the midbody in the stomach with a brief review of the literatures.

Keyword

Hyperplastic polyp; Adenocarcinoma
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