Korean J Gastrointest Endosc.  2005 Dec;31(6):399-403.

Two Cases of Adenocarcinoma Arising from Gastric Hyperplastic Polyp

  • 1Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea. jeonghy@cnuh.co.kr
  • 2Department of Pathology, Chungnam National University College of Medicine, Daejeon, Korea.


Epithelial gastric polyps can be categorized as being either hyperplastic or adenomatous. Hyperplastic polyps accounts for 75~90% of gastric polyps. In contrast to the adenomatous polyps, the potential of a malignant transformation of hyperplastic polyps was originally believed to be quite low (an incidence of 1.5~2.1%), which is considerably lower than that of an adenoma of the stomach. Most of reported cases of a hyperplastic gastric polyp with a transformation to adenocarcinoma were well differentiated histopathologically. There are few reports of a hyperplastic polyp in which malignant changes developed during the endoscopic surveillance. We report a rare case of a 1.2 cm sized moderately differentiated adenocarcinoma arising in a hyperplastic polyp on the cardia in the stomach with a brief review of the relevant literature.


Gastric hyperplastic polyp; Adenocarcinoma
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