Korean J Gastroenterol.  2001 Apr;37(4):283-286.

Two Cases of Wernicke's Encephalopathy During Management of Acute Pancreatitis

Affiliations
  • 1Department of Internal Medicine, Chonbuk National University College of Medicine, Chonju, Korea.

Abstract

The local and systemic complications of acute pancreatitis are protean. The systemic complications include pulmonary, cardiovascular, hematologic, renal, metabolic, and central nervous system abnormalities. Wernicke's encephalopathy is developed due to diencephalic and mesencehalic dysfunction of central gray structures surrounding the third and fourth ventricles by thiamine deficiency. Patients who are in fasting state, receiving parenteral nutrition, recovering from gastrointestinal surgery, being fed after a period of starvation, undergoing hemodialysis, or suffering from advanced cancer, are particularly susceptible to Wernicke's encephalopathy. Here, we report two cases of Wernicke's encephalopathy complicated during the management of acute pancreatitis.

Keyword

Acute pancreatitis; Wernicke's encephalopathy; Thiamine deficiency

MeSH Terms

Central Nervous System
Fasting
Fourth Ventricle
Humans
Pancreatitis*
Parenteral Nutrition
Renal Dialysis
Starvation
Thiamine Deficiency
Wernicke Encephalopathy*
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