J Korean Neurol Assoc.  2002 Jan;20(1):89-92.

A Case of Anti-Hu Associated Paraneoplastic Subacute Sensory Neuronopathy

Affiliations
  • 1Department of Neurology, College of Medicine, Pusan National University, Korea. dskim@pusan.ac.kr
  • 2Department of Internal Medicine, College of Medicine, Pusan National University, Korea.

Abstract

Subacute sensory neuronopathy usually occurs as a paraneoplastic syndrome, occurring most frequently in small cell lung cancer. We report a 63-year-old male presenting typical symptoms of subacute sensory neuronopathy. Electrophysiologic studies showed diffuse sensory axonal degeneration and anti-Hu antibody was positive in his serum. We reevaluated pulmonary lesions formerly diagnosed as active pulmonary tuberculosis. Chest computed tomography showed two nodules and hilar lymphadenopathy, and by percutaneous needle biopsy, small cell lung cancer was diag-nosed.

Keyword

Paraneoplastic sensory neuronopathy; Small cell lung cancer; Anti-Hu antibody

MeSH Terms

Axons
Biopsy, Needle
Humans
Lymphatic Diseases
Male
Middle Aged
Paraneoplastic Syndromes
Small Cell Lung Carcinoma
Thorax
Tuberculosis, Pulmonary
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