Korean J Gastrointest Endosc.  2005 Oct;31(4):257-262.

A Case of Hepatic Angiosarcoma Presenting as Submucosal Tumor Resulting from Gastric Invasion

• Kang HM
• Lee JN
• Kim MW
• Kim CH
• Park JH
• Yoon JH
• Kim HW
• Park SK
• Park HU
• Kim HS

Abstract

Angiosarcoma accounts for 1% of all soft tissue sarcoma. Common sites of occurrence include the skin, breast, soft tissue, and liver. It metastasizes to the lungs, bone, and spleen. The cause of hepatic angiosarcoma in the 60% of cases is unknown, although specific risk factors such as vinyl chloride, arsenic, thorotrast and external-beam irradiation have been identified. Since 1986, about eight cases of hepatic angiosarcoma have been reported in Korea, but it had not been reported in which the hepatic angiosarcoma invaded to the stomach, yet. So we report a case of histopathologically confirmed primary hepatic angiosarcoma with gastric involvement. In this case, a sixtythree-year-old female was presented with indigestion and epigastric soreness for 1 year. Endoscopic examination of the stomach revealed a submucosal tumor-like protruding mass from the antrum to angle. The mucosal surface showed severe hyperemia and shallow ulcerative change was seen. Endoscopic biopsy and percutaneous liver biopsy confirmed the diagnosis of hepatic angiosarcoma invading the gastric wall.

Keyword

Angiosarcoma; Hepatic angiosarcoma; Gastric involvement

MeSH Terms

Arsenic
Biopsy
Breast
Diagnosis
Dyspepsia
Female
Hemangiosarcoma*
Humans
Hyperemia
Korea
Liver
Lung
Risk Factors
Sarcoma
Skin
Spleen
Stomach
Thorium Dioxide
Ulcer
Vinyl Chloride
Arsenic
Thorium Dioxide
Vinyl Chloride