Korean J Gastrointest Endosc.  2005 Oct;31(4):257-262.

A Case of Hepatic Angiosarcoma Presenting as Submucosal Tumor Resulting from Gastric Invasion

  • 1department of Internal Medicine, Maryknoll Hospital, Busan, Korea. drhwpark@hananet.net
  • 2department of Pathology, Maryknoll Hospital, Busan, Korea.


Angiosarcoma accounts for 1% of all soft tissue sarcoma. Common sites of occurrence include the skin, breast, soft tissue, and liver. It metastasizes to the lungs, bone, and spleen. The cause of hepatic angiosarcoma in the 60% of cases is unknown, although specific risk factors such as vinyl chloride, arsenic, thorotrast and external-beam irradiation have been identified. Since 1986, about eight cases of hepatic angiosarcoma have been reported in Korea, but it had not been reported in which the hepatic angiosarcoma invaded to the stomach, yet. So we report a case of histopathologically confirmed primary hepatic angiosarcoma with gastric involvement. In this case, a sixtythree-year-old female was presented with indigestion and epigastric soreness for 1 year. Endoscopic examination of the stomach revealed a submucosal tumor-like protruding mass from the antrum to angle. The mucosal surface showed severe hyperemia and shallow ulcerative change was seen. Endoscopic biopsy and percutaneous liver biopsy confirmed the diagnosis of hepatic angiosarcoma invading the gastric wall.


Angiosarcoma; Hepatic angiosarcoma; Gastric involvement
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