Korean J Nucl Med.  2000 Jun;34(3):199-206.

Prognostic Value of Normal Exercise (99m)Te-MIBI Myocardial Perfusion SPECT: Comparison with Exercise Electrocardiography and Coronary Angiography

• Lee SW
• Lee JT
• Chun KA
• Kang DY
• Kim DH
• Cho YK
• Chae SC
• Lee KB

Abstract

PURPOSE: Myocardial perfusion scintigraphy is a useful technique to diagnose and to predict prognosis in patients with suspected or known coronary artery disease. The purpose of the present study is to evaluate the prognostic value of normal exercise (99m)Tc-MIRI myocardial perfusion single photon emission computed tomography (SPECT) an(l to analyze results with regard to those of exercise. electrocardiography or coronary angiography.
MATERIALS AND METHODS
We evaluated 30) patients (mean age S2+/-10 years, 166 males and 135 females) with normal exercise (99m)Tc-MIBI myocardial perfusion SPECT performed for suspected coronary artery disease. Subjects were evaluated for cardiac events and followed for 8-55 months (mean 19+/-10 months) after imaging.
RESULTS
During the follow-up period, there was no cardiac death but only one non-fatal myocardial infarction (event rate 0,21%: per year). In addition, only one patient underwent coronary revascularization. There was no significant difference in cardiac event rate between patients with positive (n=27) and negative (n-235) exercise electrocardiography (p:NS), There was no cardiac event in ]7 patients who underwent coronary angiography (4 patients with >50% luminal narrowing, 2 patients with vasospasm and 11 patients with no significant lesion).
CONCLUSION
Patients with normal exercise (99m)Tc-MIBI myocardial perfusion SPECT has a very low risk for cardiac events regardless of exercise electrocardiographic and coronary angiographic findings.

Keyword

Normal exercise myocardial perfusion scintigraphy; Prognosis; Exercise ECG; Coronary angiography

MeSH Terms

Coronary Angiography*
Coronary Artery Disease
Death
Electrocardiography*
Follow-Up Studies
Humans
Male
Myocardial Infarction
Perfusion Imaging
Perfusion*
Phenobarbital
Prognosis
Tomography, Emission-Computed, Single-Photon*
Phenobarbital