Korean Circ J.  2000 Jan;30(1):49-55. 10.4070/kcj.2000.30.1.49.

Comparison of Silent Patients with Painful Patients in Patients with Coronary Artery Stenoses during Exercise Myocardial Perfusion Scintigraphy

• Kang DY
• Lee J
• Lee SW
• Chun KA
• Cho YK
• Chae SC
• Jun JE
• Park WH
• Lee KB

• KMID: 1858430
• DOI: http://doi.org/10.4070/kcj.2000.30.1.49

Abstract

BACKGROUND AND OBJECTIVES: The angiographic profiles and myocardial ischemic variables were compared between patients with and without chest pain during exercise myocardial perfusion scintigraphy in patients with coronary artery stenoses.
MATERIALS AND METHODS
Study population were 102 consecutive patients who have significant luminal stenoses (> 50%) on coronary angiography. They underwent symptom-limited treadmill exercise test and myocardial perfusion single photon emission computed tomography (SPECT). Tc-99m methoxylisobutyl isonitrile (MIBI) was injected intravenously at rest and one minute before the termination of exercise. Tomographic images were acquired within 1 hour of tracer injection. Electrocardiographic variables, scintigraphic summed reversibility scores and angiographic profiles were compared between patients with and without chest pain during exercise.
RESULTS
Silent ischemia was noted in 52/102 (51%) of the subjects. The summed reversibility score of myocardial SPECT was not significanlty different between patients with (6.0+/-4.2) and without (5.1+/-5.0) chest pain. The extent, vessel distribution and stenosis severity of coronary artery disease were not significantly different between two groups. ST segment depression was more prominent in patients with chest pain (1.51+/-1.49 mm) than without chest pain (0.5+/-1.1 mm) during exercise stress testing.
CONCLUSION
The degree of coronary stenoses and scintigraphic myocardial ischemia was not different between patients with and without chest pain during exercise stress testing.

Keyword

Chest pain; Silent myocardial ischemia; Coronary artery stenoses; Exercise stress testing; Single-photon emission-computed tomography

MeSH Terms

Chest Pain
Constriction, Pathologic
Coronary Angiography
Coronary Artery Disease
Coronary Stenosis*
Coronary Vessels*
Depression
Electrocardiography
Exercise Test
Humans
Ischemia
Myocardial Ischemia
Perfusion Imaging*
Perfusion*
Phenobarbital
Tomography, Emission-Computed, Single-Photon
Phenobarbital