Korean J Hematol.  2001 Aug;36(3):257-261.

A Case of Waldenstrom's Macroglobulinemia Presented as a Compression Fracture of Spine

Affiliations
  • 1Department of Internal Medicine, Gachon Medical School, Gil Medical Center, Inchon, Korea.
  • 2Department of Clinical Pathology, Gachon Medical School, Gil Medical Center, Inchon, Korea.

Abstract

Waldenstrom's macroglobulinemia is a rare disease of plasmacytoid lymphocyte proliferation usually presented without bone lesion which is the common presenting symptom in multiple myeloma. We report a 50-year-old female with Waldenstrom's macroglobulinemia presented as a bony lesion without many other features common in this diesease. She was admitted with the chief complaint of low back pain and low extremity paresthesia for two months. Bone marrow biopsy and aspiration, protein and immune electrophoresis showed findings consistent with Waldenstr m's macroglobulinemia. Magnetic resonance imaging of thoracic spine showed pathologic compression fracture in T6 and T7 with posterior epidural mass at T6 to T7 level. We report this unusual case of Waldenstrom's macroglobulinemia presented as compression fracture of thoracic spine with a review of literatures.

Keyword

Waldenstr m's macroglobulinemia; Bone lesion; Compression fracture

MeSH Terms

Biopsy
Bone Marrow
Electrophoresis
Extremities
Female
Fractures, Compression*
Humans
Low Back Pain
Lymphocytes
Magnetic Resonance Imaging
Middle Aged
Multiple Myeloma
Paresthesia
Rare Diseases
Spine*
Waldenstrom Macroglobulinemia*
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