Korean J Gastrointest Endosc.  2003 Aug;27(2):76-79.

A Case of Duodenal Involvement in Waldenstrom's Macroglobulinemia

Affiliations
  • 1Department of Internal Medicine, Maryknoll Hospital, Busan, Korea. drhwpark@hananet.net
  • 2Department of Pathology, Maryknoll Hospital, Busan, Korea.

Abstract

Waldenstrom's macroglobulinemia is a disorder of malignant proliferation of plasmacytoid lymphocytes and monoclonal immunoglobulin M. However, the patients occasionally present with malabsorption and diarrhea due to deposition of extracellular periodic acid-Schiff positive homogenous eosinophilic, amorphorous, and proteinaceous materials in the villi and/or lamina propria of the duodenum. We report a 62-year-old man who, despite involvement of the duodenal mucosa, presented only with fatigue, dypnea on exertion, and anemia. Characteristic duodenoscopic and pathologic findings of this patient are described.

Keyword

Waldenstrom's macroglobulinemia; Grayish white mucosa; Duodenum
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