Korean J Gastrointest Endosc.
2003 Aug;27(2):76-79.
A Case of Duodenal Involvement in Waldenstrom's Macroglobulinemia
- Affiliations
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- 1Department of Internal Medicine, Maryknoll Hospital, Busan, Korea. drhwpark@hananet.net
- 2Department of Pathology, Maryknoll Hospital, Busan, Korea.
Abstract
- Waldenstrom's macroglobulinemia is a disorder of malignant proliferation of plasmacytoid lymphocytes and monoclonal immunoglobulin M. However, the patients occasionally present with malabsorption and diarrhea due to deposition of extracellular periodic acid-Schiff positive homogenous eosinophilic, amorphorous, and proteinaceous materials in the villi and/or lamina propria of the duodenum. We report a 62-year-old man who, despite involvement of the duodenal mucosa, presented only with fatigue, dypnea on exertion, and anemia. Characteristic duodenoscopic and pathologic findings of this patient are described.
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