Korean J Hematol.  2000 Feb;35(1):92-96.

A Case of Hairy Cell Leukemia

Affiliations
  • 1Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.
  • 2Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Abstract

Hairy cell leukemia (HCL) is a chronic B- cell disorder characterized by the presence of typical hairy cells in the peripheral blood and marrow, pancytopenia, and a variable degree of splenomegaly. Identification of typical hairy cells in the peripheral blood and demonstration of tartrate-resistant acid phosphatase (TRAP) are critical findings in HCL. Hepatic involvement of HCL is a common feature and liver biopsy show diffuse mono-nuclear cell infiltration throughout the hepatic sinusoids and in the portal areas. We report a case of hairy cell leukemia in a 52-year-old man who presented with pneumonia and hepatic infiltration with review of the literatures.

Keyword

Hairy cell leukemia; Hepatic infiltration

MeSH Terms

Acid Phosphatase
Biopsy
Bone Marrow
Humans
Leukemia, Hairy Cell*
Liver
Middle Aged
Pancytopenia
Pneumonia
Splenomegaly
Acid Phosphatase
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