Korean J Hematol.  2000 Feb;35(1):81-86.

A Case of Extrapulmonary Disseminated Tuberculosis Including Tuberculous Meningitis in combination with Acute Myelogenous Leukemia

Affiliations
  • 1Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Korea.
  • 2Department of Clinical pathology, College of Medicine, Ewha Womans University, Seoul, Korea.
  • 3Department of Anatomical pathology, College of Medicine, Ewha Womans University, Seoul, Korea.

Abstract

The occurrence of disseminated tuberculosis in combination with acute leukemia is rare. A 28 year old male undergoing induction chemotherapy for AML presented with fever of unknown origin. Upon the studies to make the diagnosis this case turned out to be disseminated tuberculosis including meningitis. The chest CT showed multiple enlarged mediastinal lymphadenopathy. The Brain CT showed noncommunicating obstructive hydrocephalus. Disseminated tuberculosis was pathologically proven by theliver, bone marrow and mediastinal lymph node biopsies. As clinical course improved, radiological lesions were completely resolved after antituberculosis therapy. It is important to consider disseminated tuberculosis for the etiology of FUO inpatient with AML who had suffered from long standing fever.

Keyword

Acute Leukemia; Tuberculous meningitis; Extrapulmonary disseminated tuberculosis

MeSH Terms

Adult
Biopsy
Bone Marrow
Brain
Diagnosis
Fever
Fever of Unknown Origin
Humans
Hydrocephalus
Induction Chemotherapy
Inpatients
Leukemia
Leukemia, Myeloid, Acute*
Lymph Nodes
Lymphatic Diseases
Male
Meningitis
Tomography, X-Ray Computed
Tuberculosis*
Tuberculosis, Meningeal*
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