J Korean Neurosurg Soc.  2008 Dec;44(6):382-384. 10.3340/jkns.2008.44.6.382.

Gas-Forming Brain Abscess Caused by Klebsiella Pneumoniae

• Cho KT
• Park BJ

• KMID: 1477499
• DOI: http://doi.org/10.3340/jkns.2008.44.6.382

Abstract

Gas forming brain abscess is a rare disease caused by Klebsiella pneumoniae occurring in patients with impaired host defense mechanism such as diabetes mellitus or liver cirrhosis. A 59-year-old man with 2-year history of diabetes mellitus and 20-year history of liver cirrhosis presented to the hospital with headache. On the day after admission, severe headache was developed and he deteriorated rapidly. Brain CT showed a non-enhanced mass including multiple air density as well as surrounding edema seen in the right occipital lobe, and isodensity air-fluid level seen in the right lateral ventricle. Despite emergent ventricular drainage and intraventricular and intravenous administration of antibiotics, his condition progressively worsened to sepsis and to death after 5 days. Bacterial culture of blood and ventricular fluids disclosed a Gram (-) rod, Klebsiella pneumoniae. In this report we review the pathogenic mechanism and its management.

Keyword

Brain abscess; Klebsiella pneumoniae; Air

MeSH Terms

Administration, Intravenous
Anti-Bacterial Agents
Brain
Brain Abscess
Diabetes Mellitus
Drainage
Edema
Headache
Humans
Klebsiella
Klebsiella pneumoniae
Lateral Ventricles
Liver Cirrhosis
Middle Aged
Occipital Lobe
Rare Diseases
Sepsis
Anti-Bacterial Agents