J Korean Acad Rehabil Med.  2009 Dec;33(6):711-714.

A Case of Combined Compressive and Vitamin B12 Deficient Myelopathy: A case report

Affiliations
  • 1Department of Rehabilitation Medicine, College of Medicine Dongguk University, Korea. bskwon@duih.org
  • 2Department of Radiology, College of Medicine Dongguk University, Korea.

Abstract

Vitamin B12 deficiency can cause myelopathy of subacute combined degeneration of lateral and dorsal column in spinal cord. When combined with compressive myelopathy, symptoms and signs of vitamin B12 deficient myelopathy could be masked. We experienced a case of forty-one year old man suffered from gait disturbance and decreased proprioception. Initially surgeons concluded his weakness resulted from myelopathy by C5-6 centrally herniated disk based on MRI and surgical decompression was performed. Gait disturbance slightly improved but decreased proprioception did not improve. Vitamin B12 deficiency was found and high signal intensity lesions were found in dorsal and lateral spinal column with review of pre-op MRI. After administration with vitamin B12 supplements, weakness and sensation of proprioception improved and follow-up MRI showed decreased signal intensity. We concluded the cause of his symptoms was combination of compressive myelopathy and vitamin B12 deficient myelopathy.

Keyword

Subacute combined degeneration; Myelopathy; Vitamin B12

MeSH Terms

Decompression, Surgical
Follow-Up Studies
Gait
Intervertebral Disc Displacement
Masks
Proprioception
Sensation
Spinal Cord
Spinal Cord Compression
Spinal Cord Diseases
Spine
Subacute Combined Degeneration
Vitamin B 12
Vitamin B 12 Deficiency
Vitamins
Vitamin B 12
Vitamins
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