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Co-Existence of Anterior and Posterior Column Lesions in Patients with Subacute Combined Degeneration

Choi K, Moon Y, Oh J

Subacute combined degeneration (SCD) of the spinal cord, which is a result of vitamin B12 deficiency, may cause irreversible neurological deficits. The lesion in the spinal cord is typically localized...
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Polyneuropathy Following Nitrous Oxide Abuse

Seo JY, Kim Y, Lee Jw, Bae JS

Nitrous oxide (N2O), an anesthetic gas, has been abused by some people for entertainment purposes. Recently, N2O (under the name of "Happy Balloon") abuse has become problematic among young people...
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A case of subacute combined degeneration of the spinal cord showing enhancement on T1-weighted MR images

Cho A, Baek S, Cho J

  • KMID: 2522469
  • J Korean Soc Emerg Med.
  • 2021 Oct;32(5):475-479.
Vitamin B12 deficiency results in the occurrence of systemic diseases in our nervous system. One of the most common manifestations of Vitamin B12 deficiency is subacute combined degeneration (SCD), which...
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Metformin Preserves Peripheral Nerve Damage with Comparable Effects to Alpha Lipoic Acid in Streptozotocin/High-Fat Diet Induced Diabetic Rats

Kim SH, Park TS, Jin HY

Background Metformin is widely marketed medication for the treatment of diabetes, but its pharmacological effect on diabetic peripheral neuropathy remains unclear. In this study, the effect of metformin on peripheral nerves...
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Subacute Combined Degeneration Caused by Nitrous Oxide Intoxication: A Report of Two Cases

Choi C, Kim T, Park KD, Lim OK, Lee JK

We report two cases of subacute combined degeneration (SCD) caused by nitrous oxide (Nâ‚‚O) gas intoxication, which is rarely reported in Korea. Two patients recreationally inhaled Nâ‚‚O gas daily for...
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Systematic Review of Vitamin B12 Regimen for Patient with Subacute Combined Degeneration of the Spinal Cord Following Nitrous Oxide Abuse

Chung JS, Choa MH, Chung SP, Park IC

PURPOSE: The purpose of this study is to evaluate the effectiveness of vitamin B12 treatment in subacute combined degeneration (SCD) caused by nitrous oxide (Nâ‚‚O) abuse. METHODS: Relevant literature was accessed...
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The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis

Nozari E, Ghavamzadeh S, Razazian N

Plasma homocysteine level and megaloblastic anemia status are two factors that can affect the quality of life of patients with multiple sclerosis (MS). We conducted this study to determine the...
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Hyperpigmentation of Both Hands due to Vitamin B12 Deficiency

Son JH, Jin H, You H, Shim WH, Kim GW, Kim HS, Ko HC, Kim MB, Kim BS

  • KMID: 2436851
  • Korean J Dermatol.
  • 2018 Aug;56(7):455-456.
No abstract available.
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Subacute Combined Degeneration in a Patient with Long-Term Oral Contraceptive Use

Kim D, Choi BK, Hong JM, Kim K, Lee JH, Choi YC

No abstract available.
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A randomized, open labeled study comparing the serum levels of cobalamin after three doses of 500 mcg vs. a single dose methylcobalamin of 1500 mcg in patients with peripheral neuropathy

Sil A, Kumar H, Mondal RD, Anand SS, Ghosal A, Datta A, Sawant SV, Kapatkar V, Kadhe G, Rao S

BACKGROUND: Vitamin B12 deficiency has been associated with peripheral neuropathy, loss of sensation in the peripheral nerves, and weakness in the lower extremities. Methylcobalamin is the most effective analogue of...
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Ameliorative effect of vitamin B12 on seminiferous epithelium of cimetidine-treated rats: a histopathological, immunohistochemical and ultrastructural study

Elsaed WM, Bedeer RF, Eladl MA

Cimetidine is an H2 receptor antagonist that has an antiandrogenic effect. It intervenes with the conversion of testosterone into estrogen in the Sertoli cells with accompanying testicular structural changes. In...
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Spontaneous Remission of Pernicious Anemia

Sul H, Moon WR, Lee HJ, Park SG, Chung CH, Park CY

Pernicious anemia is a macrocytic anemia that is caused by vitamin B12 deficiency, itself a result of the absence of intrinsic factors due to autoimmune destruction of parietal cells. We...
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Vitamin B12 Deficiency with Extreme Hyperhomocysteinemia Presenting with a Brain Ischemic Lesion

Lee SM, Suh HI, Gil YE, Kwon HM, Lim TS

No abstract available.
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Recovery of inferior alveolar nerve injury after bilateral sagittal split ramus osteotomy (BSSRO): a retrospective study

Lee CH, Lee BS, Choi BJ, Lee JW, Ohe JY, Yoo HY, Kwon YD

BACKGROUND: Bilateral sagittal split ramus osteotomy (BSSRO) is the most widely used mandibular surgical technique in orthognathic surgery and is easy to relocate the distal segments, accelerating bone repair by...
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The effects of exercise training and acute exercise duration on plasma folate and vitamin B12

Kim YN, Hwang JH, Cho YO

BACKGROUND/OBJECTIVES: Energy production and the rebuilding and repair of muscle tissue by physical activity require folate and vitamin B12 as a cofactor. Thus, this study investigated the effects of regular...
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Central Nervous System Complication due to Pernicious Anemia in a Patient with Rheumatoid Arthritis

Lee JM, Chai JW, Shin K

Pernicious anemia (PA) is an autoimmune disease characterized by atrophic gastritis and deficiency in intrinsic factor leading to impairment of vitamin B12 absorption in the ileum. Anemia is commonly found...
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Association of Vitamin B12 Deficiency and Metformin Use in Patients with Type 2 Diabetes

Ko SH, Ko SH, Ahn YB, Song KH, Han KD, Park YM, Ko SH, Kim HS

We evaluated the prevalence of vitamin B12 deficiency and associated factors in type 2 diabetes patients using metformin. A total of 799 type 2 diabetes patients using metformin was enrolled....
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Comparison of anthropometric data and clinical health indicators according to the serum vitamin B12 status in female older adults living in a rural area of Jeonla province, Korea

Kwak CS, Cho JH, Yon M

  • KMID: 2329663
  • J Nutr Health.
  • 2013 Jun;46(3):239-249.
Subclinical vitamin B12 deficiency is common in the elderly worldwide. We investigated the change of serum vitamin B12 concentration with aging and compared anthropometric data and clinical health indicators between...
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A Multicenter Retrospective Analysis of the Clinical Features of Pernicious Anemia in a Korean Population

Song IC, Lee HJ, Kim HJ, Bae SB, Lee KT, Yang YJ, Park SY, Cho DY, Kim NY, Cho IS, Jo DY

To determine the approximate incidence and clinical features of pernicious anemia in a Korean population, we retrospectively analyzed clinical data for patients with pernicious anemia who were diagnosed between 1995...
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Sequential Involvement of the Nervous System in Subacute Combined Degeneration

Minn YK, Kim SM, Kim SH, Kwon KH, Sunwoo IN

PURPOSE: Subacute combined degeneration (SCD) involves progressive degeneration of the spinal cord, optic nerve, and peripheral nerves. Vitamin B12 (VB12) is a co-factor in myelin synthesis. Because each cell that...
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