Korean J Phys Anthropol.
2010 Dec;23(4):199-206.
Microscopic Observation of Decomposition-inhibition Effect in GSE (Grapefruit Seed Extract) in Rat Liver
- Affiliations
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- 1Department of Funeral Science, College of Health Industry, Eulji University, Korea.
- 2Department of Dental Hygiene, College of Health Science, Eulji University, Korea.
- 3Electron Microscopy Laboratory, Eulji University, Korea.
- 4Department of Anatomy and Cell Biology, College of Medicine, Hanyang University, Korea. paikdj@hanyang.ac.kr
Abstract
- Regarding to preserve the cadaver, formaldehyde has been used as a major preservative. However, the usage of formaldehyde has been considered by its harmful effects such as the disturbing ordor, toxicities and limitations to use. Therefore we studied the effect of decomposition-inhibition which is a natural product, grapefruit seed extract (GSE). Concerning the preservative activity, we sacrificed 8 week old male SD rat and collected liver. Using liver tissues, we treated GSE as a time dependant manner under 37degrees, 80+/-5% humidity conditions. To confirm GSE effects, we applied light and electron microscopic analysis. In results, we observed GSE attenuated the morphological changes and putrefaction of liver tissues more than 3 days. Herein, we introduced the potential substitute of formaldehyde to preserve the cadaver as well as animal tissues.
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