Korean J Obstet Gynecol.  2010 Oct;53(10):946-951. 10.5468/kjog.2010.53.10.946.

Sarcomatoid squamous cell carcinoma of uterine cervix

• Park Y
• Cho JH
• Lee JS
• Shin JK
• Choi WJ
• Lee JH
• Paik WY

• KMID: 1453761
• DOI: http://doi.org/10.5468/kjog.2010.53.10.946

Abstract

Sarcomatoid squamous cell carcinoma (SSCC) is composed of squamous cell carcinoma element and spindle cell element, and can occur in any organ, such as the lung, skin and esophagus. But SSCC in uterine cervix is very rare. The prognosis of SSCC is poorer than squamous cell carcinoma (SCC) of uterine cervix. We report here a case of SSCC of uterine cervix with a brief review of literature.

Keyword

Sarcomatoid squamous cell carcinoma; Uterine cervix

MeSH Terms

Carcinoma, Squamous Cell
Cervix Uteri
Esophagus
Female
Lung
Prognosis
Skin

Figure

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  Fig. 1 Pelvis CT showed the LN enlargement at Lt. iliac area (arrow) and ill-defined cervical mass.

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  Fig. 2 (A) The tumor consists of squamous cell carcinoma (solid arrows). (B) Sarcomatoid component (open arrows) (H&E stain, ×100).

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  Fig. 3 Lymph node involvement by squamous cell carcinoma component (arrows heads) (H&E stain, ×100).

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  Fig. 4 Immunoperoxidase staining for cytokeratin (A) and vimentin (B). (A) The squamous cell carcinoma component (solid arrows) and sarcomatoid component (open arrows) was positive for cytokeratin (×200). (B) The sarcomatoid component (open arrows) was positive for vimentin (×200).

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  Fig. 5 (A) Four-month postoperative CT scan showed a mass of 5.4 cm in diameter extended from vaginal stump to pelvic cavity (A) and hydronephrosis of right kidney due to pelvic mass (B). (B) There were right hydronephrosis (arrow) due to right pelvic mass.

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