Korean J Urol.  2008 Mar;49(3):284-286. 10.4111/kju.2008.49.3.284.

Primary Neuroendocrine Carcinoma of the Urethra

• Lee JN
• Lee DW
• Kim YS
• Yoon GS
• Kim JS
• Yoo ES
• Kim BW

• KMID: 1204635
• DOI: http://doi.org/10.4111/kju.2008.49.3.284

Abstract

Primary neuroendocrine carcinomas are uncommon highly malignant tumors of the genitourinary tract, and they have a poor prognosis. We report here on a case of a primary neuroendocrine carcinoma of the urethra that developed after radical cystectomy and ileal conduit diversion for treating transitional cell carcinoma of the urinary bladder.

Keyword

Neuroendocrine carcinoma; Urethra

Reference

1. Mackey JR, Au HJ, Hugh J, Venner P. Genitourinary small cell carcinoma: determination of clinical and therapeutic factors associated with survival. J Urol. 1998; 159:1624–9.

2. Jo SW, Jo IC, Lee OJ, Lee SC, Kim YT, Lee HL, et al. A young man with primary small cell carcinoma of the urinary bladder. Korean J Urol. 2006; 47:556–8.

3. Bang JK, Park CM, Kim HK, Park JY. Small cell carcinoma of the kidney in a young male. Korean J Urol. 2007; 48:552–4.

4. Sylora HO, Diamond HM, Kaufman M, Straus F 2nd, Lyon ES. Primary carcinoid tumor of the urethra. J Urol. 1975; 114:150–3.

5. Vadmal MS, Steckel J, Teichberg S, Hajdu SI. Primary neuroendocrine carcinoma of the penile urethra. J Urol. 1997; 157:956–7.

6. Parekh DJ, Jung C, Roberts R, Shappell S, Smith JA Jr. Primary neuroendocrine carcinoma of the urethra. Urology. 2002; 60:1111.

7. Rudloff U, Amukele SA, Moldwin R, Qiao X, Morgenstern N. Small cell carcinoma arising from the proximal urethra. Int J Urol. 2004; 11:674–7.

8. Altintas S, Blockx N, Huizing MT, Van den Brande J, Hoekx L, Bogers JP, et al. Small-cell carcinoma of the penile urethra: a case report and a short review of the literature. Ann Oncol. 2007; 18:801–4.

9. Helpap B. Morphology and therapeutic strategies for neuroendocrine tumors of the genitourinary tract. Cancer. 2002; 95:1415–20.

10. Christopher ME, Seftel AD, Sorenson K, Resnick MI. Small cell carcinoma of the genitourinary tract: an immunohistochemical, electron microscopic and clinicopathological study. J Urol. 1991; 146:382–8.