Korean J Ophthalmol.  2007 Jun;21(2):106-110. 10.3341/kjo.2007.21.2.106.

Peripheral Anterior Synechiae and Ultrasound Biomicroscopic Parameters in Angle-Closure Glaucoma Suspects

• Yoo C
• Oh JH
• Kim YY
• Jung HR

• KMID: 1101913
• DOI: http://doi.org/10.3341/kjo.2007.21.2.106

Abstract

PURPOSE: To investigate the correlation between peripheral anterior synechia (PAS) and the quantitative anterior chamber angle parameters measured by ultrasound microscopy (UBM) in angle-closure glaucoma suspect (ACGS) eyes. METHODS: Eyes were defined ACGS as having occludable angles and intraocular pressure less than 21 mm Hg without glaucomatous optic nerve head. The gonioscopic criteria for ACGS were the trabecular meshwork invisible in 3 or more quadrants of the entire angle and the angular width less than 20 degrees by Shaffer classification. Twenty-seven eyes of 20 patients underwent anterior chamber angle and ciliary body imaging with UBM. Angle opening distance (AOD500), angle recess area (ARA), trabecular-ciliary process distance (TCPD) and trabecular-iris angle (TIA) were measured from the UBM images at each quadrant. RESULTS: The AOD500, ARA, and TIA were not significantly different between the eyes with PAS (9 eyes) and without PAS (18 eyes) at each quadrant. However, the TCPD was significantly shorter in the superior quadrant when compared with the eyes without PAS (mean: 405.3+/-70.9 micrometer vs 536.4+/-140.5 micrometer) (p<0.05). CONCLUSIONS: The results suggest that the shorter distance from trabecular meshwork to ciliary body or the anterior placement of ciliary process may play a role in the development of PAS in ACGS eyes.

Keyword

Angle-closure glaucoma; Ciliary body; Peripheral anterior synechia; Trabecular-ciliary process distance; Ultrasound biomicroscopy

MeSH Terms

Aged
Anterior Chamber/*ultrasonography
Ciliary Body/pathology/ultrasonography
Cross-Sectional Studies
Female
Follow-Up Studies
Glaucoma, Angle-Closure/pathology/*ultrasonography
Gonioscopy
Humans
Male
Microscopy, Acoustic/*methods
Middle Aged
Prognosis
Retrospective Studies
Severity of Illness Index
Trabecular Meshwork/pathology/ultrasonography

Figure

• 

  Fig. 1 Schematic representation of UBM anterior chamber angle measurement. Angle opening distance (AOD500) is defined as the length of the line drawn from the point on the corneal endothelial surface 500 µm anterior to the scleral spur to the iris surface perpendicular to the corneal endothelial surface. Trabecular-iris angle (TIA) is defined as an angle formed with the apex at the iris recess and the arms passing through the point on the meshwork 500 µm from the scleral spur and the point on the iris perpendicularly opposite. Trabecular ciliary process distance (TCPD) is defined as the distance between a point 500 µm from the scleral spur and the ciliary process on the line that is perpendicular through the iris. Angle recess area (ARA) is defined as the triangular area bordered by the anterior iris surface, corneal endothelium, and a line perpendicular to the corneal endothelium drawn to the iris surface from a point 750 µm anterior to the scleral spur.

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