Korean J Ophthalmol.  2005 Mar;19(1):29-33. 10.3341/kjo.2005.19.1.29.

Comparison of the Long-term Clinical Results of Hydrophilic and Hydrophobic Acrylic Intraocular Lenses

• Suh Y
• Oh C
• Kim HM

• KMID: 1099082
• DOI: http://doi.org/10.3341/kjo.2005.19.1.29

Abstract

This study was performed to compare the incidence of posterior capsular opacity (PCO) and refractive errors between hydrophilic (ACR6D, Corneal (R) ) and hydrophobic (MA60BM, AcrySof (R) ) acrylic intraocular lenses (IOLs) over a 3-year follow-up after phacoemulsification surgery. The patients with AcrySof (R) implanted in one eye and Corneal (R) in the other eye were categorized as Group 1 (n=28), while those with one or both eyes implanted with IOLs of the same kind were categorized as Group 2 (AcrySof (R), n=90; Corneal (R), n=95). Refractive errors were evaluated at 3 months and 3 years postoperatively. The incidence of visually significant PCO was investigated 3 years postoperatively. Postoperative refractive values at 3 months were not significantly different between the two groups. However, refractive values at 3 years were significantly different between two IOLs in both groups [AcrySof (R) -0.37 +/- 0.43D, Corneal (R) -0.62 +/- 0.58D in Group 1 (p=0.04) ; AcrySof (R) -0.38 +/- 0.52, Corneal (R) -0.68 +/- 0.54 in Group 2 (p< 0.01) ]. The incidence of visually significant PCO was 14% and 32% in Group 1, and 13% and 28% in Group 2, for the AcrySof (R) and Corneal (R) implants, respectively. The incidence of visually significant PCO of hydrophilic acrylic IOLs was higher than that of hydrophobic acrylic IOLs in the 3-year follow-up. The postoperative 3-year refractive value of Corneal (R) showed myopic shift.

Keyword

Acrylic intraocular lens; Myopic shift; Posterior capsular opacity

MeSH Terms

*Acrylic Resins
Aged
Cataract/*epidemiology/etiology
Comparative Study
Female
Follow-Up Studies
Humans
Hydrophobicity
Incidence
Lens Capsule, Crystalline/*pathology
Lens Implantation, Intraocular
*Lenses, Intraocular
Male
Middle Aged
Phacoemulsification
*Postoperative Complications
Refractive Errors/*epidemiology/etiology

Reference

1. Scaramuzza A, Fernando GT, Crayford BB. Posterior capsule opacification and lens epithelial cell layer formation: Hydroview hydrogel versus AcrySof acrylic intraocular lenses. J Cataract Refract Surg. 2001. 27:1047–1054.

2. Sundelin K, Friberg-Raid Y, Ostberg A, Sjostrand J. Posterior capsular opacification with AcrySof and polymethylmethacrylate intraocular lenses. J Cataract Refract Surg. 2001. 27:1586–1590.

3. Ram J, Kaushik S, Brar GS, Gupta A. Neodymium:YAG capsulotomy rates following phacoemulsification with implantation of PMMA, Silicone, and Acrylic intraocular lenses. Ophthalmic Surg Lasers. 2001. 32:375–382.

4. Hayashi K, Hayashi H, Nakao F, Hayashi F. Reduction in area of the anterior opening after polymethylmethacrylate, silicone and soft acrylic intraocular lens implantation. Am J Ophthalmol. 1997. 123:441–447.

5. Ursell PG, Spalton DJ, Pande MV. Anterior capsular stability in eyes with intraocular lenses made of polymethylmethacrylate, silicone and AcrySof. J Cataract Refract Surg. 1997. 23:1532–1538.

6. Nagata T, Minakata A, Watanabe I. Adhesiveness of AcrySof to a collagen film. J Cataract Refract Surg. 1998. 24:367–370.

7. Gabriel MM, Aheam DG, Chan LY, Patel AS. In vitro adherence of Pseudomonas aeruginosa to four intraocular lenses. J Cataract Refract Surg. 1998. 24:124–129.

8. Ursell PG, Spalton DJ, Pande MV, et al. Relationship between intraocular lens biomaterials and posterior capsular opacification. J Cataract Refract Surg. 1998. 24:352–360.

9. Barret GD, Constable IL, Stewart AD. Clinical results of hydrogel lens implantation. J Cataract Refract Surg. 1986. 12:623–631.

10. Nishi O, Nishi K. Preventing posterior capsular opacification by creating a discontinuous sharp bend in the capsule. J Cataract Refract Surg. 1999. 25:521–526.

11. Hollick EJ, Spaton DJ, Ursell PG, et al. The effect of polymethylmethacrylate, silicone, and polyacrylic intraocular lenses on posterior capsular opacification 3 years after cataract surgery. Ophthalmology. 1999. 106:49–54.

12. Hollick EJ, Spalton DJ, Ursell PG, Pande MV. Biocompatibility of poly(methylmethacrylate), silicone and AcrySof intraocular lenses: randomized comparison of the cellular reaction on the anterior lens surface. J Cataract Refract Surg. 1998. 24:361–366.

13. Schauersberger J, Kruger A, Abela C, et al. Course of postoperative inflammation after implantation of 4 types of foldable intraocular lenses. J Cataract Refract Surg. 1999. 25:1116–1120.

14. Hollick EJ, Spalton DJ, Ursell PG. Surface cytologic features on intraocular lenses: can increased biocompatibility have disadvantages? Arch Ophthalmol. 1999. 117:872–878.

15. Nishi O, Nishi K, Imanishi M. Synthesis of interleukin-1 and prostaglandin E2 by lens epithelial cells of human cataracts. Br J Ophthalmol. 1992. 76:338–341.

16. Nishi O, Nishi K, Fujiwara T, et al. Effects of the cytokines on the proliferation of and collagen synthesis by human cataract lens epithelial cells. Br J Ophthalmol. 1996. 80:63–68.

17. Peng Q, Visessook N, Apple DJ, et al. Surgical prevention of posterior capsular opacification. Part 3: intraocular lens optic barrier effect as a second line of defense. J Cataract Refract Surg. 2000. 26:198–213.

18. Buehl W, Findl O, Menapace R, et al. Effect on an acrylic intraocular lens with a sharp posterior optic edge on posterior capsular opacification. J Cataract Refract Surg. 2002. 28:1105–1111.

19. Schauersberger J, Amon M, Kruger A, et al. Comparison of the biocompatibility of 2 foldable intraocular lenses with sharp optic edges. J Cataract Refract Surg. 2001. 27:1579–1585.

20. Nishi O, Nishi K. Preventive effect of a second-generation silicone intraocular lens on posterior capsular opacification. J Cataract Refract Surg. 2002. 28:1236–1240.

21. Nishi O, Nishi K. Effect of the optic size of a single-piece acrylic intraocular lens on posterior capsule opacification. J Cataract Refract Surg. 2003. 29:348–353.

22. Neumann AC, Cobb B. Advantages and limitations of current soft intraocular lenses. J Cataract Refract Surg. 1987. 15:257–263.

23. Kim JY, Cha HW. The clinical results of hydrophilic acrylic lens. J Korean Ophthalmol Soc. 2001. 42:1562–1570.

24. Yu AK, Kwan KY, Chan DH, Fong DY. Clinical features of 46 eyes with calcified hydrogel intraocular lenses. J Cataract Refract Surg. 2001. 27:1596–1606.

25. Werner L, Apple DJ, Escobar-Gomez M, et al. Postoperative deposition of calcium on the surfaces of a hydrogel intraocular lens. Ophthalmology. 2000. 107:2179–2185.