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Clinical and Imaging Features of Cystic Fibrosis in Korean Children

Kwon YJ, Yoo SY, Jeon TY, Kim JH, Park JE

Cystic fibrosis (CF) is a fatal hereditary disorder that primarily affects Caucasians and is rare in Asian populations, including Koreans. Diagnosing CF is often challenging and delayed owing to its...
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Clinical Study of Endobronchial Tuberculosis

A clinical study was carried out on 30 patients confirmed with endobronchial tuberculosis who have visited the Department of Internal Medicine, Han Yang University Hospita1 during the period from January...
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Kennedy’s Disease with Chronic Low Back Pain and Muscle Weakness

Kim JY, Park YS, Chang HJ, Park JG, Cho ES, Kim DH, Lee JH, Kim SJ

Kennedy’s disease (KD) or bulbospinal muscular atrophy is an uncommon x-linked recessive genetic disorder. Its diagnosis is challenging due to its wide array of clinical manifestations and difficulty distinguishing it...
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Exploring the Molecular and Developmental Dynamics of Endothelial Cell Differentiation

Shin YJ, Lee JH

The development and differentiation of endothelial cells (ECs) are fundamental processes with significant implications for both health and disease. ECs, which are found in all organs and blood vessels, play...
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Cost-Effectiveness Analysis of Germline and Somatic BRCA Testing in Patients With Advanced Ovarian Cancer

Jang J, Kim Y, Kim JH, Cho SM, Lee KA

Background: BRCA testing is necessary for establishing a management strategy for ovarian cancer. Several BRCA testing strategies, including germline and somatic testing, are implemented in clinical practice in Korea. We...
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Investigation of Effective Critical Value Thresholds for Laboratory Tests in Clinical Laboratories

Jang H, Jang J, Kang H, Rim JH, Lim JB

The establishment and prompt reporting of critical values to patient care providers is one of the crucial requirements of clinical laboratories. Each laboratory is expected to individually establish the thresholds...
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Homeostatic Model Assessment of Insulin Resistance as a Potential Screening Test for NonAlcoholic Fatty Liver Disease in Korean Adults without Diabetes

Lee H, Lee JH

Background: Non-alcoholic fatty liver disease (NAFLD) prevalence rapidly increases worldwide and may lead to end-stage liver disease such as cirrhosis or hepatocellular carcinoma. This study aimed to examine the relationship...
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Effects of Home Based Serious Game Training (Brain Talk™) in the Elderly With Mild Cognitive Impairment: Randomized, a Single-Blind, Controlled Trial

Lim EH, Kim DS, Won YH, Park SH, Seo JH, Ko MH, Kim GW

Mild cognitive impairment (MCI) increases with aging society. Serious games may be effective in improving cognitive function in patients with MCI; however, research on their effects remains insufficient. This study...
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The Efficacy of Enhanced Magnetic Resonance Imaging and Computed Tomography in Extensive Infected Deep Burn with Pus Collection

Kim JH, Lee YC, Chung CM, Park MC

Purpose: In the case of a chronically unhealed 3rd or 4th degree burn, the lesion may involve the deep structures, and may be deeper and wider than what is visible...
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Unmet dental care needs and related factors among pregnant women: analysis based on data from 2019 Korean Community Health Survey

Sun AY, Park HJ, Lee JH

Objectives: This study aims to identify the factors affecting unmet dental care needs in pregnant women in Korea, and analyze the results. Methods: The study used original data from the 2019...
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Comparison of Coffee Stain Removal Effects of Commercial Whitening Toothpaste in Sound and Demineralized Teeth In Vitro

Min JH

Background: The size of the tooth whitening market and toothpaste market is increasing worldwide. The purpose of this in vitro study is to confirm and compare the coffee stain removal...
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Clinical Utility of Sero-Immunological Responses Against SARS-CoV-2 Nucleocapsid Protein During Subsequent Prevalence of Wild-Type, Delta Variant, and Omicron Variant

Lee B, Ko JH, Baek JY, Kim H, Huh K, Cho SY, Kang CI, Chung DR, Peck KR, Kang ES

As nucleocapsid protein of severe acute respiratory syndrome coronavirus 2 is immunogenic but not targeted in vaccines, it could be useful in distinguishing natural infection from vaccination. We aimed to...
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The effect of polishing procedure and pH on the color change of denture base resin.

Kim JH, Kim JW, Hwang SY, Kim HJ

The purpose of this study is to investigate the effect of polishing procedure and pH on the color change of denture base resin. Heat-cured denture resin specimens (10 x 10...
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Licochalcone D Inhibits Skin Epidermal Cells Transformation through the Regulation of AKT Signaling Pathways

Hwang SY, Wi K, Yoon G, Lee CJ, Lee SI, Jung Jg, Jeong HW, Kim JS, Choi CH, Na CS, Shim JH, Lee MH

Cell transformation induced by epidermal growth factor (EGF) and 12-O-tetradecanoylphorbol-13-acetate (TPA) is a critical event in cancer initiation and progression, and understanding the underlying mechanisms is essential for the development...
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Establishing a Reference Interval for Flow Cytometry-Based NK Activity (FC-NKA) Assay in Healthy Korean Population

Kang H, Choi AR, Ryu JH, Oh EJ

Background: Flow cytometry (FC)-based natural killer cell activity (NKA) assays are commonly used in clinical laboratories. As low or no NKA is indicative of hemophagocytic lymphohistiocytosis (HLH), the precise determination...
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East Asian Gynecologic Oncology Trial Group (EAGOT): founding history and future perspective

Enomoto T, Okamoto A, Kim JH, Lai CH, Wu X, Kim YM

Racial and regional differences exist in morbidity, histology, drug response, toxicity, and prognosis of gynecologic cancer. However, most large-scale phase III studies have been conducted in Western countries, and these...
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Licochalcone H Targets EGFR and AKT to Suppress the Growth of Oxaliplatin -Sensitive and -Resistant Colorectal Cancer Cells

Lee SO, Lee MH, Kwak AW, Lee JY, Yoon G, Joo SH, Choi YH, Park JW, Shim JH

Treatment of colorectal cancer (CRC) has always been challenged by the development of resistance. We investigated the antiproliferative activity of licochalcone H (LCH), a regioisomer of licochalcone C derived from...
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Systematization of food and nutrition education content based on national kindergarten curriculum: a qualitative formative study

Kim JH, Shim E, Baik E

Objectives: This study is intended to develop a curriculum for kindergarten food and nutrition education aimed...
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Socioeconomic Disparities in the Association Between All-Cause Mortality and Health Check-Up Participation Among Healthy Middle-Aged Workers: A Nationwide Study

Yun B, Oh J, Choi J, Rozek LS, Park H, Sim J, Kim Y, Lee J, Yoon JH

Background: This study assessed the relationship between non-participation in health checkups and all-cause mortality and morbidity, considering socioeconomic status. Methods: Healthy, middle-aged (35–54 years) working individuals who maintained either self-employed or...
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Optimizing Mannitol Use in Managing Increased Intracranial Pressure: A Comprehensive Review of Recent Research and Clinical Experiences

Kim JH, Jeong H, Choo YH, Kim M, Ha EJ, Oh J, Shim Y, Kim SB, Jung HG, Park SH, Kim JO, Kim J, Kim HS, Lee S

Mannitol, derived from mannose sugar, is crucial in treating patients with elevated intracranial pressure (ICP). Its dehydrating properties at the cellular and tissue levels increase plasma osmotic pressure, which is...
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