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Surveillance Systems for Assessing Vaccine Safety: Possibilities and Limitations

Lee JK

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Efficacy of Olaparib in Treatment-Refractory, Metastatic Breast Cancer with Uncommon Somatic BRCA Mutations Detected in Circulating Tumor DNA

Yoon JK, Ahn J, Kim S, Kim HP, Kang Jk, Bang D, Lim Y, Kim TY

Poly(ADP-ribose) polymerase inhibitors have been shown dramatic responses in patients with BRCAness. However, clinical studies have been limited to breast cancer patients with germline mutations. Here, we describe a patient...
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Impact of denosumab on aortic arch calcification in kidney transplant recipients

Park WY, Yang J, Kwon JK, Lee HJ, Kim Y, Paek JH, Jin K, Han S

Background: Aortic arch calcification (AoAC) is associated with cardiovascular disease in kidney transplant recipients (KTRs). Recent research reported that Denosumab, a potent antiresorptive agent, might affect to AoAC in hemodialysis...
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Systematic Diagnosis and Treatment Principles for Acute Fracture-Related Infections

Choi JS, Kwon JH, Kang SH, Ryu YK, Choi WS, Oh JK, Cho JW

Acute fracture-related infection (FRI) is a common and serious complication of fracture treatment. The clinical symptoms of the patient and the results of the serological, radiological, and histopathologi-cal examinations can...
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Isolated testicular tuberculosis in a kidney transplantation recipient

Yang J, Kwon JK, Lee HJ, Paek JH, Kim Y, Park WY, Jin K, Choe M, Han S

Genitourinary tuberculosis (Tb) is a rare form of extrapulmonary Tb. Especially, isolated testicular Tb is extremely uncommon. The precise diagnosis of testicular Tb might be challenging due to ambiguous clinical...
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Herpes Zoster Accompanying Odontogenic Inflammation: A Case Report with Literature Review

Lee S, Kim M, Huh JK, Kim JY

Herpes zoster is caused by reactivation and multiplication of a latent varicella-zoster virus infection. Reactivation can frequently occur in older adults and immunosuppressed individuals. It is hypothesized that this is...
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Comparative Analysis of Anticancer and Antibacterial Activities among Seven Trametes Species

Nguyen HTK, Lee J, Park Y, Park HJ, Ahn SK, Kim JK, Kang DK, Kim M, Ahn C, Kim C, Choi J

Species in the genus Trametes (Basidiomycota, Polyporales) have been used in natural medicine for a long time. Many studies reported that mycelia or fruiting bodies of Trametes spp. exhibited effects...
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Cremastranone-Derived Homoisoflavanes Suppress the Growth of Breast Cancer Cells via Cell Cycle Arrest and Caspase-Independent Cell Death

Choi Y, Park S, Lee S, Shin HE, Kwon S, Choi JK, Lee MH, Seo SY, Lee Y

Breast cancer is the most common cancer and a frequent cause of cancer-related deaths among women wordlwide. As therapeutic strategies for breast cancer have limitations, novel chemotherapeutic reagents and treatment...
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Comparison Between Two Different Second-Generation Parathyroid Hormone Assays

Kang JK, Jeon JH, Park JH, Kee SJ, Choi HW

Background: Accurate measurement of parathyroid hormone (PTH) levels is crucial for the diagnosis and treatment of hyperparathyroidism and hypoparathyroidism. Given the existence of various PTH forms in the bloodstream, it...
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Usefulness of Direct Peroral Cholangioscopy Using a Multibending Ultraslim Endoscope for the Management of Intrahepatic Bile Duct Lesions (with Videos)

Lee WM, Moon JH, Lee YN, Min CW, Shin IS, Myeong JH, Kim HK, Yang JK, Lee TH

Background/Aims: Peroral cholangioscopy (POC) has been used to assess intrahepatic duct (IHD) lesions but with a limited role. A new multibending (MB) ultraslim endoscope has been designed to improve POC...
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Cost-Utility Analysis for Colorectal Cancer Screening According to the Initiating Age of National Cancer Screening Program in Korea

Bae S, Lee K, Kim BC, Jun JK, Choi KS, Suh M

Background: This study aimed to identify the most cost-effective strategy for colorectal cancer screening using the fecal immunochemical test (FIT), focusing on screening initiation age in Korea. Methods: We designed Markov...
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Hematocrit Determination using a Volumetric Absorptive Microsampling Technique in Patients with Pancreatic Cancer

Jung Y, Yoo S, Kang M, Lim H, Lee MH, Ryu JK, Lee J

Background: Hematocrit is usually measured from venous blood collected by invasive venipuncture. This study was performed to determine hematocrit accurately and precisely using minimally invasive volumetric absorptive microsampling (VAMS) technique. Such...
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The Relationship between Depression Severity and Prefrontal Hemodynamic Changes in Adolescents with Major Depression Disorder: A Functional Near-infrared Spectroscopy Study

Shin JE, Lee YS, Park SY, Jeong MY, Choi JK, Cha JH, Lee YJ

  • KMID: 2553617
  • Clin Psychopharmacol Neurosci.
  • 2024 Feb;22(1):118-128.
  • doi: 10.9758/cpn.23.1073
Objective: Numerous studies have identified hemodynamic changes in adults with major depressive disorder (MDD) by using functional near-infrared spectroscopy (fNIRS). However, studies on adolescents with MDD are limited. As adolescence...
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Usefulness of therapeutic drug monitoring with tacrolimus and mycophenolate in kidney transplantation

Park DJ, Park M, Lim J, Kim MH, Hwang JK, Kim HD, Ban TH, Choi BS, Lee J

Background: Tacrolimus and mycophenolate (MPA) are main maintenance immunosuppressive agents in kidney transplantation (KT). Therapeutic drug monitoring (TDM) of tacrolimus is useful to obtain a balance between allograft function and...
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A case of crescentic immunoglobulin A nephropathy associated with Henoch-Schonlein purpura after kidney transplantation

Kim NS, Kim JK, Oh JS

Crescentic glomerulonephritis (GN) is a glomerular disease in which renal function deteriorates rapidly within days to months, and without appropriate treatment, it can progress to end-stage renal disease (ESRD). Henoch-Schonlein...
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The Age and Sex-specific Quality of Life by Chronic Disease Using the EQ-5D Index : Based on the 2017-2019 Korea National Health and Nutrition Examination Survey

Chae GJ, Park SH, Song SA, Lee JK, Hong Jm, Song JS, Kim NJ

Objectives: This study analyzed the decline in quality of life according to age in the chronic disease patient group, quantified it as a quantitative index, and compared it by sex...
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Engineering of Cell Derived-Nanovesicle as an Alternative to Exosome Therapy

Jang HJ, Shim KS, Lee J, Park JH, Kang SJ, Shin YM, Lee JB, Baek W, Yoon JK

BACKGROUND Exosomes, nano-sized vesicles ranging between 30 and 150 nm secreted by human cells, play a pivotal role in long-range intercellular communication and have attracted significant attention in the field...
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Rituximab induction therapy in deceased donor kidney transplantation: a case series analysis

Kim HD, Ban TH, Hwang I, Choi BS, Kim BS, Park M, Park DJ, Lim J, Kim MH, Hwang JK

Background: This retrospective observational study presents a case series involving deceased donor kidney transplant (DDKT) recipients who received rituximab induction therapy, aiming to assess the impact of rituximab. Methods: Among the...
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Comparative Analysis of Clinical Outcomes Using Propensity Score Matching: Coronavirus Disease 2019 vs. Seasonal Influenza in Korea

Sim JK, Lee HS, Yang J, Gwack J, Kim BI, Cha Jo, Min KH, Lee YS, obotSARI(I

Background: The advent of the omicron variant and the formulation of diverse therapeutic strategies marked a new epoch in the realm of coronavirus disease 2019 (COVID-19). Studies have compared the...
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Anti-cancer effect of fenbendazole-incorporated PLGA nanoparticles in ovarian cancer

Chang CS, Ryu JY, Choi JK, Cho YJ, Choi JJ, Hwang JR, Choi JY, Noh JJ, Lee CM, Won JE, Han HD, Lee JW

Objective Fenbendazole (FZ) has potential anti-cancer effects, but its poor water solubility limits its use for cancer therapy. In this study, we investigated the anti-cancer effect of FZ with different drug...
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