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Systematization of food and nutrition education content based on national kindergarten curriculum: a qualitative formative study

Kim JH, Shim E, Baik E

Objectives: This study is intended to develop a curriculum for kindergarten food and nutrition education aimed...
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A comparative study of impression methods using stock tray and intraoral scanner in a completely edentulous

Park JH, Kim JH, Seo JM, Lee JJ, Park YH

In complete denture fabrication, accurate preliminary impressions are crucial for obtaining an accurate final impression. However, it can be challenging in cases of atypical arch shapes. This case report compares...
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Self-Symptom Checker for COVID-19 Control and Symptom Management

Ahn SJ, Kim JD, Yoon JH, Park JH

Background: Breaking the chain of disease transmission from overseas is necessary to control new infectious diseases such as coronavirus disease 2019 effectively. In this study, we developed a mobile app...
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Novel Histone Deacetylase 6 Inhibitor Confers Anti-inflammatory Effects and Enhances Gut Barrier Function

Lee JY, Ma HW, Kim JH, Park IS, Son M, Ryu KH, Shin J, Kim SW, Cheon JH

Background/Aims: The purpose of the current study was to examine the anti-inflammatory effects of CKD-506, a novel histone deacetylase 6 inhibitor, on human peripheral blood mononuclear cells (PBMCs) and CD4+...
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Realistic Estimation of COVID-19 Infection by Seroprevalence Surveillance of SARS-CoV-2 Antibodies: An Experience From Korea Metropolitan Area From January to May 2022

Jeong IH, Kim JH, Kwon MJ, Kim J, Huh HJ, Kim B, Lee J, Nam Jh, Kang ES

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, leading to the coronavirus disease 2019 (COVID-19) pandemic. Because a significant proportion of the COVID-19 confirmed cases were concentrated...
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Complex Hypersensitivity and Irritation Reaction (CHAIR) Phenomenon after Cyanoacrylate Closure of Varicose Vein

Joh JH, Joo SH

Cyanoacrylate glue is a non-thermal, non-tumescent agent used to treat saphenous reflux. It was introduced to overcome heat-related discomfort and complications. Multiple randomized controlled trials using this therapy have demonstrated...
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Epidemiology and Characteristics of Pediatric Respiratory Virus Infection From 2017 to 2019 Focusing on Human Coronavirus: A Retrospective Study of a Single Center in Northwestern Gyeonggi-do

Park H, Cho KW, Chung LY, Kim JM, Song JH, Kim KN

Purpose: A change is expected in the pattern of respiratory viruses including human coronavirus (HCoV) after the coronavirus disease 2019 (COVID-19) outbreak. Accordingly, identifying the distribution of respiratory viruses before...
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A quantitative comparison of oral microbiota using various sample collection methods: a pilot study

Im SU, Kim JH, Song KB, Choi YH

Objectives: This study aimed to compare each strain’s number of microorganisms found in oral samples collected using various collection methods. Methods: Twenty-two adults aged 40 and above participated in the study....
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Corchorus olitorius Ethanolic Extract has Anti-inflammatory and Wound Healing Effects in vitro

Lee K, Park JH, Lee DH, Jo SM, Park Y, Kang TJ

This study aimed to investigate the anti-inflammatory and wound healing effects of Corchorus olitorius cultivated in smart farms....
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Preclinical Study on Biodistribution of Mesenchymal Stem Cells after Local Transplantation into the Brain

Bashyal N, Kim MG, Jung JH, Acharya R, Lee YJ, Hwang WS, Choi JM, Chang DY, Kim SS, Suh-Kim H

Therapeutic efficacy of mesenchymal stem cells (MSCs) is determined by biodistribution and engraftment in vivo. Compared to intravenous infusion, biodistribution of locally transplanted MSCs are partially understood. Here, we performed a...
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Complications of the Central Nervous System in Pediatric Patients With Common Cold Coronavirus Infection During 2014–2019

Park H, Kim KR, Huh HJ, Yoon Y, Park E, Cho J, Lee J, Lee J, Kim JH, Kim YJ

Background: In pediatric patients, the common cold coronavirus (ccCoV) usually causes mild respiratory illness. There are reports of coronavirus causing central nervous system (CNS) infection in experimental animal models. Some...
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A case of intestinal Behcet’s disease after kidney transplantation

Shin HS, Park M, Kim SM, Kim Jh, Cho H, Kwon SK, Kim HY

Behcet’s disease is a multisystemic, inflammatory disease with a chronic relapsing course. Intestinal Behcet’s disease is characterized by intestinal symptoms and typical colon ulcerations observed by endoscopic examination. Here, we...
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In vitro evaluation of the antitumor activity of axitinib in canine mammary gland tumor cell lines

Lee HG, Lim GH, An JH, Park SM, Seo KW, Youn HY

Background: Axitinib, a potent and selective inhibitor of vascular endothelial growth factor (VEGF) receptor (VEGFR) tyrosine kinase 1,2 and 3, is used in chemotherapy because it inhibits tumor angiogenesis by...
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Comparison of blood parameters according to fecal detection of Mycobacterium avium subspecies paratuberculosis in subclinically infected Holstein cattle

Ha S, Kang S, Jung M, Kim SB, Lee HG, Park HT, Lee JH, Choi KC, Park J, Kim UH, Yoo HS

Background: Mycobacterium avium subspecies paratuberculosis (MAP) causes a chronic and progressive granulomatous enteritis and economic losses in dairy cattle in subclinical stages. Subclinical infection in cattle can be detected using serum...
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Effects of oxypeucedanin hydrate isolated from Angelica dahurica on myoblast differentiation in association with mitochondrial function

Song EJ, Heo JW, Jang JH, Kwon YJ, Jeong YH, Kim MJ, Kim SE

Purpose: Mitochondria play a crucial role in preserving skeletal muscle mass, and damage to mitochondria leads to muscle mass loss. This study investigated the effects of oxypeucedanin hydrate, a furanocoumarin...
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Promoter-Specific Variants in NeuroD1 and H3K4me3 Coincident Regions and Clinical Outcomes of Small Cell Lung Cancer

Yoo SS, Lee S, Choi JE, Hong MJ, Do SK, Lee JH, Lee WK, Park JE, Lee YH, Choi SH, Seo H, Lee J, Lee SY, Cha SI, Kim CH, Kang HG, Park JY

Background: Neurogenic differentiation 1 (NeuroD1) is a representative small cell lung cancer (SCLC) transcription regulator involved in the carcinogenesis and behavior of SCLC. Histone modifications play an important role in transcription,...
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Effects of polygalacin D extracted from Platycodon grandiflorum on myoblast differentiation and muscle atrophy

Song EJ, Heo JW, Jang JH, Kim E, Jeong YH, Kim MJ, Kim SE

Purpose: The balance between synthesis and degradation of proteins plays a critical role in the maintenance of skeletal muscle mass. Mitochondrial dysfunction has been closely associated with skeletal muscle atrophy...
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Rapid Targeted Sequencing Using Dried Blood Spot Samples for Patients With Suspected Actionable Genetic Diseases

Kim MJ, Kim SY, Lee JS, Kang S, Park LJ, Choi W, Jung JY, Kim T, Park SS, Ko JM, Seong MW, Chae JH

Background: New genome sequencing technologies with enhanced diagnostic efficiency have emerged. Rapid and timely diagnosis of treatable rare genetic diseases can alter their medical management and clinical course. However, multiple...
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Etiology and Clinical Characteristics of Community-Acquired Pneumonia in Korean Children During the PreCOVID-19 Period, 2015-2020

Suh JH, Ahn B, Song SH, Choi S, Choi SH, Lee H, Han MS, Park JY, Choi EH, Yun KW

Background: There have been many epidemiologic studies on community-acquired pneumonia (CAP) among children, most of which had substantial limitations. This study investigated the etiologic distribution and clinical characteristics of CAP...
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Identification of Genes Involved in EGF-induced Apoptosis Using CRISPR/Cas9 Knockout Screening: Implications for Novel Therapeutic Targets in EGFR-Overexpressing Cancers

Kim JS, Lee JH, Jeon SR, Kim Y, Jeon SH, Wu HG

Purpose Exogenous epidermal growth factor (EGF) causes apoptosis in EGF receptor (EGFR)–overexpressing cell lines. The apoptosis-inducing factors could be a therapeutic target. We aimed to determine the mechanism of EGF-induced...
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