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The Study of beta-Glucuronidase Activity in Selected Orthopaedic Disease

Yoo CI, Suh KT, Kim CY, Moon HC, Yoon PJ

  • KMID: 2025522
  • J Korean Rheum Assoc.
  • 1997 Jul;4(2):147-154.
OBJECTIVES: The purpose of this study was to get help in order to diagnose orthopaedic disease, measure its activity and determine treatment plan by measuring the beta-glucuronidase activity in urine,...
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The comparison of bilateral bone mineral density in postmenopausal women

Cha J, Ko M, Min J, Yoon PJ, Yoon H, Chung Yj, Song JY, Kim MR

  • KMID: 2523761
  • J Menopausal Med.
  • 2021 Dec;27(3):s11.
Objectives: The aim of this study is to determine whether there is a difference between right and left femur bone mineral density (BMD) in postmenopausal women. Methods: We performed a retrospective...
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Effects of Nitric Oxide Synthesis Inhibition on the Blood Pressure Response to Bradykinin in Rats

Yeum CH, Yang MJ, Jun JY, Yoon PJ, Moon SH, Kim JH, Lee JU

  • KMID: 2079020
  • Korean J Nephrol.
  • 1998 Sep;17(5):667-672.
Bradykinin has been known to elicit a pressor effect when administered centrally, and a depressor effect when administered peripherally. The present study was aimed at investigating whether the blood pressure...
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Central Hypotensive Effects of Imipramine in Anesthetized Rats

Yoon PJ, Chio HS, Yeum CH

BACKGROUND: One of prominent cardiovascular effects of imipramine is postural hypotension. The present study was to verify whether imipramine has a central hypotensive action and futher to investigate its mechanism...
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Altered Vascular Response to the K+induced Vasorelaxation in Aortic Smooth Muscle of Renal Hypertensive Rats

Jun JY, Yeum CH, Yoon PJ, Liee JH, Choi HH, Park YW, Kim JH

BACKGROUND: An increase of the extracellular K+concentrations up to about 8 mM in the isolated vessels causes relaxation in pre-contracted state. In order to elucidate the mechanisms of K+induced relaxation...
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Altered Dilator Responses to Heptanol and Octanol in Aorta from Renal Hypertensive Rats

Hyun SY, Hyun S, Jun JY, Yoon PJ, Choi HH, Chung JH, Kim HL, Yeum CH

  • KMID: 1337397
  • Korean J Nephrol.
  • 2006 Sep;25(5):727-735.
BACKGROUND: Cells rely on gap junctions for intercellular communication, which is important for growth and contractility. The present study was conducted to test the hypothesis that contractile responses in aortic...
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Modulation of Baroreflexes in Hypertensive Rats

Choi S, Kim JH, Sun JM, Whi HW, Choi SJ, Jun JY, Yoon PJ, Chung JH, Kim HI, Yeum CH

  • KMID: 2307162
  • Korean J Nephrol.
  • 2009 Nov;28(6):545-551.
PURPOSE: Baroreceptor reflex regulation has been shown to reset towards a higher blood pressure level. This study was designed to assess alterations of chronotropic baroreflexes in two-kidney, one clip (2K1C)...
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Role of Tyrosine Kinases in 5-HT-Induced Vascular Contraction in Two-Kidney, One Clip Hypertensive Rats

Yeum CH, Kim JS, Jun JY, Kim JH, Liee JH, Yoon PJ

  • KMID: 2254581
  • Korean J Nephrol.
  • 2000 Jan;19(1):40-48.
Tyrosine kinases have been implicated in vascular smooth muscle cell proliferation and contraction. The involvement of tyrosine kinases in 5-hydroxytryptamine (5-HT)-induced contractile response of the isolated aorta was examined in...
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Inhibition of Pacemaker Activity of Interstitial Cells of Cajal by Hydrogen Peroxide via Activating ATP-sensitive K(+) Channels

Choi S, Parajuli S, Cheong HS, Paudyal DP, Yeum CH, Yoon PJ, Jun JY

  • KMID: 1512913
  • Korean J Physiol Pharmacol.
  • 2007 Feb;11(1):15-20.
To investigate whether hydrogen peroxide (H2O2) affects intestinal motility, pacemaker currents and membrane potential were recorded in cultured interstitial cells of Cajal (ICC) from murine small intestine by using a...
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Effects of Endogenous Nitric Oxide Synthesis Inhibition on the Depressor Response to Intracerebroventricular Calcium

Yeum CH, Moon IK, Jun JY, Liee JH, Cheon KB, Yoon PJ

BACKGROUND: Aside from its well known peripheral antihypertensive effects, calcium also lowers blood pressure, when administered into the cerebral ventricle. The present study was aimed to determine whether the central...
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Pressor Responses to Intracerebroventricular Infusion of Hypertonic NaCl in Renal Hypertensive Rats

Yeum CH, Park CH, Jun JY, Kim JH, Liee JH, Hong SP, Yoon PJ

BACKGROUND: The sodium concentration in the central nervous system may play an important role in cardiovascular function and body fluid regulation. The purpose of this investigation was to examine the...
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Role of Prostaglandins on the Renin-Angiotensin System in Normotensive and Hypertensive Rats

Yoon PJ, Jung M, Kim JS, Jun JY, Yeum CH

BACKGROUND: Prostaglandin system is known to participate in manifestation of the renin-angiotensin system. However, role of prostaglandins on the renin-angiotensin system in development of hypertension is not well established. This...
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Inwardly Rectifying K+ Currents in Gastric Myocytes of Guinea-pig

Jun JY, Yeum CH, Yoon PJ, Jang IY, Cho NS, Cho SH, Kong ID, Kim TW, So I, Kim KW

  • KMID: 1614860
  • Korean J Physiol Pharmacol.
  • 2002 Feb;6(1):47-56.
To identify the presence of inwardly rectifying K+ channels and its characteristics, membrane currents were measured using a whole-cell patch clamp from isolated gastric myocytes of guinea-pig. Change of external...
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(-)-Epigallocatechin Gallate Inhibits the Pacemaker Activity of Interstitial Cells of Cajal of Mouse Small Intestine

Kim KY, Choi SJ, Jang HJ, Zuo DC, Shahi PK, Parajuli S, Yeum CH, Yoon PJ, Choi S, Jun JY

The effects of (-)-epigallocatechin gallate (EGCG) on pacemaker activities of cultured interstitial cells of Cajal (ICC) from murine small intestine were investigated using whole-cell patch-clamp technique at 30degrees C and...
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Nonadrenergic Noncholinergic Response in Fundic Strips of Guinea Pig Stomach and Its Modulation by Substance P

Heo GS, Chang SJ, Park CG, Kim MW, Jang IY, Kim JH, Shin MK, Yeum CH, Yoon PJ, Jun JY

  • KMID: 1142410
  • Korean J Gastroenterol.
  • 2003 May;41(5):358-365.
BACKGROUND/AIMS: In a gastric fundic strip, electrical field stimulation (EFS) evokes TTX-sensitive biphasic responses, consisting firstly of cholinergic contraction followed by a transient relaxation. It is well known that...
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Effects of Tamoxifen on the Voltage-dependent Ionic Currents in Mouse Colonic Smooth Muscle Cells

Lee DM, Chang SJ, Park CG, Kim MW, Lim GH, Choi S, Yeum CH, Yoon PJ, Jun JY

  • KMID: 772862
  • Korean J Gastroenterol.
  • 2005 Nov;46(5):388-395.
BACKGROUND/AIMS: Tamoxifen is a widely used anticancer drug for breast cancer with frequent gastrointestinal side effects. Changes in gastrointestinal motility is associated with altered activities of membrane ion channels....
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Involvement of Thromboxane A2 in the Modulation of Pacemaker Activity of Interstitial Cells of Cajal of Mouse Intestine

Kim JH, Choi SJ, Yeum CH, Yoon PJ, Choi S, Jun JY

Although many studies show that thromboxane A2 (TXA2) has the action of gastrointestinal (GI) motility using GI muscle cells and tissue, there are no reports on the effects of TXA2...
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Interplay of Hydrogen Sulfide and Nitric Oxide on the Pacemaker Activity of Interstitial Cells of Cajal from Mouse Small Intestine

Yoon PJ, Parajuli S, Zuo DC, Shahi PK, Oh HJ, Shin HR, Lee MJ, Yeum CH, Choi S, Jun JY

We studied whether nitric oxide (NO) and hydrogen sulfide (H2S) have an interaction on the pacemaker activities of interstitial cells of Cajal (ICC) from the mouse small intestine. The actions...
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Role of Tyrosine Kinases in Norepinephrine-Induced Vascular Contraction in Renal Hypertensive Rats

Yeum CH, Jun JY, Yoon PJ, Shin MK, Cho HH, Jang JS, Hong SP, Yeum CH

BACKGROUND AND OBJECTIVES: Protein tyrosine kinases appear to be involved in the signal transduction mechanisms, which result in vascular smooth muscle contraction, as well those required in cell growth. The...
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Effects of Nitric Oxide Synthesis Inhibition on the Depressor Response of Atrial Natriuretic Peptide in Rats

Kim H, Jeong SA, Yoo IJ, Kim JS, Choi S, Jun JY, Yoon PJ, Kim MY, Hong SP, Yeum CH

BACKGROUND AND OBJECTIVES: It has been suggested that nitric oxide (NO) and atrial natriuretic peptide (ANP) share a final common pathway for vascular smooth muscle relaxation. The aim of the...
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