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The high dosage of earthworm (Eisenia andrei) extract decreases cell proliferation and neuroblast differentiation in the mouse hippocampal dentate gyrus

Yan BC, Yoo KY, Park JH, Lee CH, Choi JH, Won MH

Earthworm extract has shown anticancer characteristics. In the present study, we examined the effect of chronic treatment with a high dose of earthworm (Eisenia andrei) extract (EE) on cell proliferation...
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Comparison of alpha-synuclein immunoreactivity in the spinal cord between the adult and aged beagle dog

Ahn JH, Choi JH, Park JH, Yan BC, Kim IH, Lee JC, Lee DH, Kim JS, Shin HC, Won MH

Alpha-synuclein (alpha-syn) is a presynaptic protein that is richly expressed in the central and peripheral nervous systems of mammals, and it is related to the pathogenesis of Parkinson's disease and...
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Efficacy and Safety of the Safe Triangular Working Zone Approach in Percutaneous Vertebroplasty for Spinal Metastasis

Yan BC, Fan YF, Tian QH, Wang T, Huang ZL, Song HM, Li Y, Jiao L, Wu CG

Objective: This study aimed to assess the technical feasibility, efficacy, and safety of the safe triangular working zone (STWZ) approach applied in percutaneous vertebroplasty (PV) for spinal metastases involving the...
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Neuroprotective effects of tanshinone I from Danshen extract in a mouse model of hypoxia-ischemia

Lee JC, Park JH, Park OK, Kim IH, Yan BC, Ahn JH, Kwon SH, Choi JH, Kim JD, Won MH

Hypoxia-ischemia leads to serious neuronal damage in some brain regions and is a strong risk factor for stroke. The aim of this study was to investigate the neuroprotective effect of...
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Accelerated and Exacerbated Effects of High Dietary Fat on Neuronal Damage Induced by Transient Cerebral Ischemia in the Gerbil Septum

Cheon SH, Yan BC, Chen BH, Park JH, Ahn JH, Kim IH, Lee JC, Park YS, Kim MJ, Lee YL, Cho JH, Won MH

BACKGROUND: Obesity induced by high-fat diet (HFD) is one of the most widespread metabolic disorders in current society. However, there has been little research regarding the effects of HFD-induced obesity...
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Comparison of arylalkylamine N-acetyltransferase and melatonin receptor type 1B immunoreactivity between young adult and aged canine spinal cord

Ahn JH, Park JH, Kim IH, Lee JC, Yan BC, Yong MS, Lee CH, Choi JH, Yoo KY, Hwang IK, Moon SM, Shin HC, Won MH

Melatonin affects diverse physiological functions through its receptor and plays an important role in the central nervous system. In the present study, we compared immunoreactivity patterns of arylalkylamine N-acetyltransferase (AANAT),...
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Systemic administration of low dosage of tetanus toxin decreases cell proliferation and neuroblast differentiation in the mouse hippocampal dentate gyrus

Yan BC, Kim IH, Park JH, Ahn JH, Cho JH, Chen BH, Lee JC, Choi JH, Yoo KY, Lee CH, Cho JH, Kim JD, Won MH

  • KMID: 2312107
  • Lab Anim Res.
  • 2013 Sep;29(3):148-155.
In the present study, we investigated the effect of Tetaus toxin (TeT) on cell proliferation and neuroblast differentiation using specific markers: 5-bromo-2-deoxyuridine (BrdU) as an exogenous marker for cell proliferation,...
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