- Regulation of p53 Genes by Ferritin Light Chain: Preliminary Study
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Yi SY
- KMID: 1973943
- Ewha Med J.
- 2008 Jun;31(1):9-14.
- doi: 10.12771/emj.2008.31.1.9
No abstract available in English. -
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- P53 expression in hepatocellular carcinoma: influence on the radiotherapeutic response of the hepatocellular carcinoma
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Lee YR, Park SY
- KMID: 2351022
- Clin Mol Hepatol.
- 2015 Sep;21(3):230-231.
- doi: 10.3350/cmh.2015.21.3.230
No abstract available. -
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- Expression of p53 and MDM-2 Protein in Cervical Neoplasia
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Chung CW, Shin YK, Park CW, Kim CJ, Cho TI, Park ES
- KMID: 2261546
- Korean J Obstet Gynecol.
- 1999 Oct;42(10):2264-2269.
OBJECTIVES: MDM-2 is an oncoprotein that inhibits p53 tumor suppressor protein. Amplication and over- expression of its protein have been observed in human malignancies, and these abnormalities have a role... -
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- Patterns of p53 expression in phyllodes tumors of the breast: an immunohistochemical study
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Kim CJ, Kim WH
- KMID: 1421998
- J Korean Med Sci.
- 1993 Oct;8(5):325-328.
- doi: 10.3346/jkms.1993.8.5.325
Authors performed an immunohistochemical analysis using monoclonal antibody to p53 protein on 15 cases of benign and malignant phyllodes tumor of the breast along with a review of other conventional... -
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- Relation between p53 Protein Overexpression and Survival of Gastric Cancer Patients Who Underwent Surgery and Early Postoperative Intraperitoneal Chemotherapy
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Ku KB, Park SH, Kwon OK, Cheong HY, Yu W
- KMID: 2211237
- J Korean Surg Soc.
- 2008 Nov;75(5):296-301.
PURPOSE: In spite of curative surgery and early postoperative intraperitoneal chemotherapy, the prognosis of patients with gastric cancer involving the serosal surface is poor. The aim of this study was... -
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- p41-Arc, a regulatory subunit of Arp2/3 complex, can induce premature senescence in the absence of p53 and Rb
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Yun UJ, Park SE, Shin DY
- KMID: 1015457
- Exp Mol Med.
- 2011 Jul;43(7):389-392.
- doi: 10.3858/emm.2011.43.7.042
Cellular senescence is a tumor-suppressive process instigated by proliferation in the absence of telomere replication, by cellular stresses such as oncogene activation, or by activation of the tumor suppressor proteins,... -
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- p53 and DNA-dependent protein kinase catalytic subunit independently function in regulating actin damage-induced tetraploid G1 arrest
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Chae HD, Kim SY, Park SE, Kim J, Shin DY
- KMID: 1245266
- Exp Mol Med.
- 2012 Mar;44(3):236-240.
- doi: 10.3858/emm.2012.44.3.018
We previously reported that the p53 tumor suppressor protein plays an essential role in the induction of tetraploid G1 arrest in response to perturbation of the actin cytoskeleton, termed actin... -
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- The Role of TWIST in Ovarian Epithelial Cancers
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Kim K, Park EY, Yoon MS, Suh DS, Kim KH, Lee JH, Shin DH, Kim JY, Sol MY, Choi KU
- KMID: 1719562
- Korean J Pathol.
- 2014 Aug;48(4):283-291.
- doi: 10.4132/KoreanJPathol.2014.48.4.283
BACKGROUND: Epithelial-mesenchymal transition (EMT) is associated with tumor hypoxia. EMT is regulated, in part, by the action of TWIST, which inhibits of E-cadherin expression and may interfere with the p53... -
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- Expression of the GLUT1 and p53 Protein in Atypical Mucosal Lesions Obtained from Gastric Biopsy Specimens
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Do IG, Kim YW, Park YK
- KMID: 1593159
- Korean J Pathol.
- 2006 Feb;40(1):32-38.
BACKGROUND: The diagnosis of atypical mucosal lesions by performing hematoxylin-eosin staining is too subjective, and it is also subject to considerable inter-observer variation. There is a need for reliable immunohistochemical... -
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- p53 Expression in a Malignant Mesothelioma Patient during Seven-Year Follow-up
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Koo SM, Uh ST, Kim DW, Kim KU, Kim YK
- KMID: 2320518
- Tuberc Respir Dis.
- 2014 Jun;76(6):284-288.
Malignant mesothelioma (MM) is the aggressive tumor of serosal surfaces. There are crude pathogenetic results regarding the biology of MM. Coordinated upregulations of p53 gene expression are shown in malignancies.... -
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- Clinical Relevance of p53 Immunohistochemical Stain in the Differential Diagnosis Between Pediatric Aplastic Anemia and Refractory Cytopenia of Childhood
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Park SH, Chi HS, Cho YU, Jang S, Park CJ, Im HJ, Seo JJ
- KMID: 2373519
- Ann Lab Med.
- 2016 Mar;36(2):174-176.
- doi: 10.3343/alm.2016.36.2.174
No abstract available. -
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- Involvement of JNK-initiated p53 accumulation and phosphorylation of p53 in pseudolaric acid B induced cell death
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Gong X, Wang M, Tashiro SI, Onodera S, Ikejima T
- KMID: 1110127
- Exp Mol Med.
- 2006 Aug;38(4):428-434.
A terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL) assay was used to determine that apoptosis causes HeLa cell death induced by pseudolaric acid B. The c-Jun N-terminal kinase (JNK) inhibitor... -
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- Uncoupling Protein 2 (UCP2) and p53 Expression in Invasive Ductal Carcinoma of Breast
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Won KY, Kim GY, Kim YW, Lim SJ, Song JY
- KMID: 2277532
- Korean J Pathol.
- 2010 Dec;44(6):565-570.
BACKGROUND: Uncoupling protein 2 (UCP2) is a recently identified mitochondrial inner membrane anion carrier and a negative regulator of reactive oxygen species production. In this study, we evaluated the characteristics... -
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- Mutations of p53 Tumor Suppressor Gene in Spontaneous Canine Mammary Tumors
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Lee CH, Kweon OK
- KMID: 1097349
- J Vet Sci.
- 2002 Dec;3(4):321-325.
Mutation of the p53 tumor suppressor gene has been related in the pathogenesis of numerous human and canine cancers, including breast cancers and mammary tumors. We have investigated exons 5-8... -
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- Immunohistochemical analysis of p53 protein expression in benign and malignant skin tumors using a panel of anti-p53 antibodies
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Ro YS, Kim JH
- KMID: 1422004
- J Korean Med Sci.
- 1993 Oct;8(5):361-366.
- doi: 10.3346/jkms.1993.8.5.361
The expression of p53 in a variety of benign and malignant skin lesions has been first assessed in frozen sections and then compared with the results obtained in corresponding paraffin-embedded... -
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- Sequence analysis of canine LINE-1 elements and p53 gene in canine transmissible venereal tumor
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Choi YK, Kim CJ
- KMID: 1097345
- J Vet Sci.
- 2002 Dec;3(4):285-292.
LINEs (long interspersed nuclear elements or long interspersed repeated DNA elements) contains two open reading frames (ORFs), ORF1 and ORF2. We analysed the ORF2 located in the 5' region to... -
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- Mdm2 and p53 Expression in Radiation-Induced Sarcomas of the Head and Neck: Comparison with De Novo Sarcomas
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Song MJ, Song JS, Roh JL, Choi SH, Nam SY, Kim SY, Kim SB, Lee SW, Cho KJ
- KMID: 2381317
- Korean J Pathol.
- 2014 Oct;48(5):346-350.
- doi: 10.4132/KoreanJPathol.2014.48.5.346
BACKGROUND: The pathogenesis of radiation-induced sarcomas (RISs) is not well known. In RIS, TP53 mutations are frequent, but little is known about Mdm2-p53 interaction, which is a recent therapeutic target... -
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- Association of p53 Expression with Metabolic Features of Stage I Non-Small Cell Lung Cancer
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Kang SM, Koh WJ, Suh GY, Chung MP, Han J, Kim H, Kwon OJ, Um SW
- KMID: 2319623
- Tuberc Respir Dis.
- 2011 Dec;71(6):417-424.
BACKGROUND: Recent evidences have revealed metabolic functions of p53 in cancer cells; adaptation or survival to metabolic stress and metabolic shift toward oxidative phosphorylation. However, further studies in clinical setting... -
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- p53 Prevents Immature Escaping from Cell Cycle G2 Checkpoint Arrest through Inhibiting cdk2-dependent NF-Y Phosphorylation
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Yun UJ, Park HD, Shin DY
- KMID: 2166051
- Cancer Res Treat.
- 2006 Dec;38(4):224-228.
PURPOSE: Recent studies have suggested that p53 regulates the G2 checkpoint in the cell cycle and this function is required for the maintenance of genomic integrity. In this study, we... -
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- The Expression of c-erbB-2, EGFR, p53 and Ki-67 in Ovarian Borderline Tumors and Carcinomas of the Ovary
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Min KW, Park MH
- KMID: 1521623
- Korean J Pathol.
- 2007 Oct;41(5):296-306.
BACKGROUND: An ovarian surface epithelial tumor is a heterogenous disease, and various biological and molecular factors are important for its development and progression. Several findings support EGFR or c-erbB-2 as... -
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