Tuberc Respir Dis.  1997 Aug;44(4):930-934.

A Case of Thrombocytopenia and Purpura Induced by Rifamnpin, Pyrazinamide, and Ciprofloxacin

Abstract

Drug-induced thrombocytopenia and purpura have boon developed by many various agents. Rifampin and Pyrazinamide have been known as bactericidal antituberculous drugs, but, the above side effects have been a problem. Especially, hematologic side effects art fatal to patients occasionally. Rifampin-induced thrombocytopenia and purpura have been well known, also, pyrazinamide-induced thrombocytopenia have been reported. A new quilonone agent Ciprofloxacin, has been commonly used in clinics now, but it's side effects are not known well. So, we report a case of a 23-year-old female with thrombocytopenia and purpura after taking Rifampin, Pyrazinamide, and Ciprofloxacin as antituberculous agents.

Keyword

Thrombocytopenia; Purpura; Rifampin; Pyrazinamide; Ciprofloxacin

MeSH Terms

Ciprofloxacin*
Female
Humans
Purpura*
Pyrazinamide*
Rifampin
Thrombocytopenia*
Young Adult
Ciprofloxacin
Pyrazinamide
Rifampin
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