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9 results

Functional Expression of P2Y Receptors in WERI-Rb1 Retinoblastoma Cells

Kim NH, Park KS, Sohn JH, Yeh BI, Ko CM, Kong ID

  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):61-66.
P2Y receptors are metabotropic G-protein-coupled receptors, which are involved in many important biologic functions in the central nervous system including retina. Subtypes of P2Y receptors in retinal tissue vary according...
Ca(2+)-induced Ca2+ Release from Internal Stores in INS-1 Rat Insulinoma Cells

Choi KJ, Cho DS, Kim JY, Kim BJ, Lee KM, Kim SH, Kim DK, Kim SH, Park HS

  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):53-59.
The secretion of insulin from pancreatic beta-cells is triggered by the influx of Ca2+ through voltage-dependent Ca2+ channels. The resulting elevation of intracellular calcium ([Ca2+]i) triggers additional Ca2+ release from...
Inhibitory Effects of Corni Fructus Extract on Angiogenesis and Adipogenesis

Hwang JH, Kim JD

  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):43-51.
Natural products in Chonnam, Korea were screened via anti-angiogenesis experiments, and 1 candidate product was identified, Corni fructus, which exerted dose-dependent inhibitory effects against angiogenesis, adipogenesis, and cell adhesion. C....
Spontaneous Contractions Augmented by Cholinergic and Adrenergic Systems in the Human Ureter

Lee HW, Baak CH, Lee MY, Kim YC

  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):37-41.
Interstitial cells of Cajal (ICC) evoke pacemaker activities in many tissues. The purpose of this study was to investigate the relationship between interstitial cell and pacemaker activity in the human...
Extracellular Nucleotides Can Induce Chemokine (C-C motif) Ligand 2 Expression in Human Vascular Smooth Muscle Cells

Kim JI, Kim HY, Kim SM, Lee SA, Son YH, Eo SK, Rhim BY, Kim K

  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):31-36.
To understand the roles of purinergic receptors and cellular molecules below the receptors in the vascular inflammatory response, we determined if extracellular nucleotides up-regulated chemokine expression in vascular smooth muscle...
Microarray Analysis of Gene Expression Profiles in Response to Treatment with Melatonin in Lipopolysaccharide Activated RAW 264.7 Cells

Ban JY, Kim BS, Kim SC, Kim DH, Chung JH

  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):23-29.
Melatonin, which is the main product of the pineal gland, has well documented antioxidant and immune-modulatory effects. Macrophages produce molecules that are known to play roles in inflammatory responses. We...
Quercetin Inhibits alpha3beta4 Nicotinic Acetylcholine Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes

Lee BH, Hwang SH, Choi SH, Shin TJ, Kang J, Lee SM, Nah SY

  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):17-22.
Quercetin mainly exists in the skin of colored fruits and vegetables as one of flavonoids. Recent studies show that quercetin, like other flavonoids, has diverse pharmacological actions. However, relatively little...
Anti-inflammatory Activity of 1-docosanoyl Cafferate Isolated from Rhus verniciflua in LPS-stimulated BV2 Microglial Cells

Lee JW, Cheong IY, Kim HS, Lee JJ, Lee YS, Kwon YS, Kim MJ, Lee HJ, Kim SS, Chun W

  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):9-15.
Although various derivatives of caffeic acid have been reported to possess a wide variety of biological activities such as protection of neuronal cells against excitotoxicity, the biological activity of 1-docosanoyl...
Involvement of ROS in Curcumin-induced Autophagic Cell Death

Lee YJ, Kim NY, Suh YA, Lee C

  • Korean J Physiol Pharmacol.
  • 2011 Feb;15(1):1-7.
Many anticancer agents as well as ionizing radiation have been shown to induce autophagy which is originally described as a protein recycling process and recently reported to play a crucial...

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