- Are Solifenacin and Ramosetron Really Ideal to Treat Irritable Bowel Syndrome?: Author's Reply
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Suzuki H, Matsuzaki
- KMID: 2325961
- J Neurogastroenterol Motil.
- 2012 Oct;18(4):459-459.
No abstract available. -
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- Are Solifenacin and Ramosetron Really Ideal to Treat Irritable Bowel Syndrome?
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Chang FY
- KMID: 2325960
- J Neurogastroenterol Motil.
- 2012 Oct;18(4):457-458.
No abstract available. -
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- Neurotoxic Effects of Tetrahydroisoquinolines and Underlying Mechanisms
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Surh YJ, Kim HJ
- KMID: 1460701
- Exp Neurobiol.
- 2010 Sep;19(2):63-70.
- doi: 10.5607/en.2010.19.2.63
Tetrahydropapaveroline (THP), a neurotoxic tetrahydroisoquinoline alkaloid formed by condensation between dopamine and dopaldehyde, has been speculated to cause Parkinson's disease and also to contribute to alcohol dependence. Having two catechol... -
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- Inhibition of tumor necrosis factor-alpha mRNA expression by a limited series of tetrahydroisoquinolines in mouse peritoneal macrophages
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Jung TH, Lee YS, Kang YJ, Lee BK, Ko YS, Seo HG, Chung SY, Lee DH, Yun-Choi H, Chang KC
- KMID: 1917026
- Korean J Physiol Pharmacol.
- 2000 Aug;4(4):325-331.
Tumor necrosis factor-alpha (TNF-alpha) plays important roles in inflammatory responses. Some of tetrahydroisoquinoline (THI) compounds exhibited to inhibit iNOS expression in animal studies and RAW 264.7 cells, but the action of THI on... -
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- CKD-712, (S)-1-(alpha-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, Inhibits the NF-kappaB Activation and Augments Akt Activation during TLR4 Signaling
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Lee J, Yang EJ, Shin JS, Kim DH, Lee SS, Choi IH
- KMID: 2150730
- Immune Netw.
- 2011 Dec;11(6):420-423.
- doi: 10.4110/in.2011.11.6.420
Since CKD-712 has been developed as an anti-inflammatory agent, we examined the effect of CKD-712 during TLR4 signaling. Using HEK293 cells expressing TLR4, CKD-712 was pre-treated 1 hr before LPS... -
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- The Efficacy of Short-term Administration of Revaprazan on Gastroesophageal Reflux Symptoms: Comparison with Half Dose Esomeprazole, a Pilot Study
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Lee HM, Kim BW, Kim JS, Im EJ, Kim JI, Kang BK, Ji JS, Lee BI, Choi H
- KMID: 2305175
- Korean J Helicobacter Up Gastrointest Res.
- 2012 Mar;12(1):23-26.
- doi: 10.7704/kjhugr.2012.12.1.23
BACKGROUND/AIMS: Revaprazan, an acid pump antagonist, is a kind of gastric acid suppressant and is prescribed for the treatment of peptic ulcers and gastritis. However, the efficacy of revaprazan on... -
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- Effect of Acid Pump Antagonist (Revaprazan, Revanex(R)) on the Result of 13C Urea Breath Test in the Patients with Helicobacter pylori Associated Peptic Ulcer Disease
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Park SY
- KMID: 991460
- Korean J Gastroenterol.
- 2011 Jan;57(1):1-2.
- doi: 10.4166/kjg.2011.57.1.1
No abstract available. -
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- Effect of Desmopressin with Anticholinergics in Female Patients with Overactive Bladder
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Han YK, Lee WK, Lee SH, Yang DY, Kim H
- KMID: 2315483
- Korean J Urol.
- 2011 Jun;52(6):396-400.
PURPOSE: The aim of this study was to evaluate the effect of desmopressin combined with anticholinergics on daytime frequency and urgency in female patients with overactive bladder (OAB). MATERIALS AND METHODS:... -
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- Rationale for the Use of Anticholinergic Agents in Overactive Bladder With Regard to Central Nervous System and Cardiovascular System Side Effects
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Cetinel B, Onal B
- KMID: 2315935
- Korean J Urol.
- 2013 Dec;54(12):806-815.
PURPOSE: Central nervous system (CNS) and cardiovascular system (CVS) side effects of anticholinergic agents used to treat overactive bladder (OAB) are underreported. Hence, this review aimed to focus on the... -
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- A Matched Case-Control Study of a Novel Acid-Pump Antagonist and Proton-Pump Inhibitor for the Treatment of Iatrogenic Ulcers Caused by Endoscopic Submucosal Dissection
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Kim YG, Jang BI, Kim TN
- KMID: 2167202
- Gut Liver.
- 2010 Mar;4(1):25-30.
BACKGROUND/AIMS: Revaprazan, a novel acid-pump antagonist, and proton-pump inhibitors (PPIs) have pH-independent effects on ulcer healing. The addition of a PPI promotes the cell restitution rate as well as vessel... -
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- Effects of Tamsulosin, Solifenacin, and Combination Therapy for the Treatment of Ureteral Stent Related Discomforts
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Lim KT, Kim YT, Lee TY, Park SY
- KMID: 2315443
- Korean J Urol.
- 2011 Jul;52(7):485-488.
PURPOSE: To evaluate the effect of tamsulosin, solifenacin, and combination therapy of two agents in improving the lower urinary tract symptoms of patients with indwelling double-J ureteral stents. MATERIALS AND METHODS:... -
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- Efficacy of Solifenacin on Irritable Bowel Syndrome With Diarrhea: Open-label Prospective Pilot Trial
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Fukushima , Suzuki H, Matsuzaki , Kiyosue A, Hibi T
- KMID: 2325931
- J Neurogastroenterol Motil.
- 2012 Jul;18(3):317-323.
BACKGROUND/AIMS: Solifenacin, a muscarinic type 3 receptor antagonist, is used to treat overactive bladder in adults. The aim of this study is to examine the efficacy of solifenacin on the... -
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- Efficacy and Safety of Solifenacin Succinate for Urinary Difficulty in Brain Lesion: Multicenter Prospective Study
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Bok SK, Lim JH, Cho KH, Choi ES, Kim SS, Lee YJ, Park NK
- KMID: 2270744
- Brain Neurorehabil.
- 2012 Sep;5(2):75-81.
- doi: 10.12786/bn.2012.5.2.75
OBJECTIVE: We studied the efficacy and safety of solifenacin for urinary difficulty in brain lesion from multicenter prospective study. METHOD: Eighty patients with brain lesion who visited from 5 multicenter department... -
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- Characterization of Bladder Selectivity of Antimuscarinic Agents on the Basis of In Vivo Drug-Receptor Binding
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Yamada S, Kuraoka S, Osano A, Ito Y
- KMID: 2232961
- Int Neurourol J.
- 2012 Sep;16(3):107-115.
The in vivo muscarinic receptor binding of antimuscarinic agents (oxybutynin, solifenacin, tolterodine, and imidafenacin) used to treat urinary dysfunction in patients with overactive bladder is reviewed. Transdermal administration of oxybutynin... -
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- A Proton Pump Inhibitor's Effect on Bone Metabolism Mediated by Osteoclast Action in Old Age: A Prospective Randomized Study
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Jo Y, Park E, Ahn SB, Jo YK, Son B, Kim SH, Park YS, Kim HJ
- KMID: 2234066
- Gut Liver.
- 2015 Sep;9(5):607-614.
- doi: 10.5009/gnl14135
BACKGROUND/AIMS: Proton pump inhibitors (PPIs) act by irreversibly binding to the H+-K+-ATPase of the proton pump in parietal cells and may possibly affect the vacuolar H+-ATPase in osteoclasts. METHODS: We investigated... -
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- Impact of Lower Urinary Tract Symptoms/Benign Prostatic Hyperplasia Treatment with Tamsulosin and Solifenacin Combination Therapy on Erectile Function
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Seo DH, Kam SC, Hyun JS
- KMID: 2315650
- Korean J Urol.
- 2011 Jan;52(1):49-54.
PURPOSE: To examine the effects on erectile function of concomitant treatment with an alpha-blocker (tamsulosin) and an antimuscarinic agent (solifenacin) in patients with lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia... -
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- Efficacy of Anticholinergics for Chronic Prostatitis/Chronic Pelvic Pain Syndrome in Young and Middle-Aged Patients: A Single-Blinded, Prospective, Multi-Center Study
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Kim DS, Kyung YS, Woo SH, Chang YS, Kim HJ
- KMID: 2232813
- Int Neurourol J.
- 2011 Sep;15(3):172-175.
PURPOSE: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) exhibits variable lower urinary tract symptoms (LUTS). The aim of this study was to evaluate the incidence of LUTS and the efficacy of... -
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- Major clinical research advances in gynecologic cancer in 2015
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Suh DH, Kim M, Kim HJ, Lee KH, Kim JW
- KMID: 2374256
- J Gynecol Oncol.
- 2016 Nov;27(6):e53.
- doi: 10.3802/jgo.2016.27.e53
In 2015, fourteen topics were selected as major research advances in gynecologic oncology. For ovarian cancer, high-level evidence for annual screening with multimodal strategy which could reduce ovarian cancer deaths... -
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- Effect of Improvement in Lower Urinary Tract Symptoms on Sexual Function in Men: Tamsulosin Monotherapy vs. Combination Therapy of Tamsulosin and Solifenacin
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Ko K, Yang DY, Lee WK, Kim SW, Moon DG, Moon KH, Park NC, Park JK, Son HC, Lee SW, Hyun JS, Park K
- KMID: 2069779
- Korean J Urol.
- 2014 Sep;55(9):608-614.
- doi: 10.4111/kju.2014.55.9.608
PURPOSE: To evaluate how much the improvement of lower urinary tract symptoms (LUTS) affects sexual function and which storage symptoms or voiding symptoms have the greatest effect on sexual function. MATERIALS... -
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- Effect of Acid Pump Antagonist (Revaprazan, Revanex(R)) on Result of 13C Urea Breath Test in Patients with Helicobacter pylori Associated Peptic Ulcer Disease
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Oak JH, Chung WC, Jung SH, Choi KH, Kim EJ, Kang BK, Kang B, Kong SE, Paik CN, Lee KM
- KMID: 991462
- Korean J Gastroenterol.
- 2011 Jan;57(1):8-13.
- doi: 10.4166/kjg.2011.57.1.8
BACKGROUND/AIMS: Revaprazan (Revanex(R)) is a novel proton pump inhibitor (PPI) that has a somewhat different effect on proton pump compared with the other PPI's, also (called as 'acid pump antagonist').... -
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