- Effect of Tetraethylammonium on the Contractile Reponse in the Isolated Rat Phrenic: Hemidiaphra
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Lee HJ, Lee KS, Song YK, Kim TY, Choi BK
- KMID: 2237810
- Korean J Anesthesiol.
- 1996 Jan;30(1):7-14.
- doi: 10.4097/kjae.1996.30.1.7
BACKGROUND: Recently, the phannacologic and therapeutic significance of various types of potassium channels are being realized. Thus it was attempted to delineate the role of voltage-gated K+ -channels on the... -
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- Effect of K+ channel Blocker on Vasodilation by Halothane
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Cho SY, Suh JK, Chon SU
- KMID: 2013181
- Korean J Anesthesiol.
- 1995 Jun;28(6):747-751.
- doi: 10.4097/kjae.1995.28.6.747
Halothane is a popular inhalation anesthetics in practice, which has been reported to cause a vasodilation through a direct depressant action on vascular smooth muscle, or by an indirect attenuation... -
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- Tetraethylammonium-induced Epileptiform Activity and its Modification by GABAA Antagonist in the Rat Visual Cortex
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Choi BJ
- KMID: 2329312
- J Korean Child Neurol Soc.
- 2005 Nov;13(2):137-143.
PURPOSE: The goal of this study was to investigate the effect of tetraethylammonium (TEA) on the excitability of visual cortex, and observe the induction of epileptiform activity. Also, it was... -
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- Inhibitory Effects of Norepinephrine on the Potassium Current of Rat Medial Vestibular Nuclear Neurons
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Jeong HS, Jang MJ, Huang M, Huh HR, Cho KH, Kim BC, Park JS
- KMID: 1626909
- J Korean Neurol Assoc.
- 2005 Jun;23(3):363-367.
BACKGROUND: This study aimed to explore the effects of norepinephrine on the potassium currents of rat medial vestibular nuclear neurons by using the whole-cell patch clamp technique. METHODS: Sprague-Dawley rats... -
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- The Effect of Tetraethylammonium Chloride on the Impulse Conduction Block by bupivacaine
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Lee SJ, Kim BJ, Choi H, Lee SW, Kil HY, Yoon YJ
- KMID: 2236922
- Korean J Anesthesiol.
- 1994 Nov;27(11):1541-1550.
- doi: 10.4097/kjae.1994.27.11.1541
Potassium channel blockers slow depolarization, broaden the action potential, and thus pro- mote the open and inactivated Na+ channel states. The ability of local anesthetics to reduce the amplitude of... -
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- Effects of Ginkgolide B on the Neuronal Excitability of Medial Vestibular Nuclear Neurons in the Rat
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Jeong HS, Kim JS, Kim BC, Lim YC, Kim JH, Park JS
- KMID: 2274969
- Chonnam Med J.
- 2002 Sep;38(3):195-201.
This study was designed to investigate the effects of the ginkgolide B on the neuronal excitability ofthe rat vestibular nuclear neurons by whole cell patch clamp technique. When cells were... -
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- Effects of Cyclic Nucleotide-Gated Channels in Vestibular Nuclear Neurons
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Heo T, Jang S, Jeong HS, Park JS
- KMID: 2172224
- Chonnam Med J.
- 2011 Dec;47(3):155-159.
- doi: 10.4068/cmj.2011.47.3.155
This study was designed to investigate the effects an 8-Br-cGMP on the neuronal activity of rat vestibular nuclear cells. Sprague-Dawley rats aged 14 to 16 days were decapitated under ether... -
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- Effects of K+ channel modulators on extracellular K+ accumulation during ischemia in the rat hippocampal slice
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Choi JK, Chun BG, Ryu PD
- KMID: 2285186
- Korean J Physiol Pharmacol.
- 1997 Dec;1(6):681-690.
Loss of synaptic transmission and accumulation of extracellular K+((K+)o) are the key features in ischemic brain damage. Here, we examined the effects of several K+ channel modulators on the early ischemic changes in... -
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- Characterization of Ionic Currents in Human Neural Stem Cells
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Lim CG, Kim SS, Suh-Kim H, Lee YD, Ahn SC
- KMID: 1838349
- Korean J Physiol Pharmacol.
- 2008 Aug;12(4):131-135.
- doi: 10.4196/kjpp.2008.12.4.131
The profile of membrane currents was investigated in differentiated neuronal cells derived from human neural stem cells (hNSCs) that were obtained from aborted fetal cortex. Whole-cell voltage clamp recording revealed... -
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- Two types of voltage-dependent outward potassium currents in smooth muscle cells of rabbit basilar artery
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Kang TM, So I, Uhm DY, Kim KW
- KMID: 1554553
- Korean J Physiol Pharmacol.
- 1997 Apr;1(2):169-183.
We have investigated the two types of voltage-dependent outward potassium (K) currents, i.e. delayed rectifier K current (I-K(V)) and 'A-like' transient outward K current (I-to) with patch-clamp technique in single smooth muscle cells... -
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- Altered Vascular Response to the K+induced Vasorelaxation in Aortic Smooth Muscle of Renal Hypertensive Rats
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Jun JY, Yeum CH, Yoon PJ, Liee JH, Choi HH, Park YW, Kim JH
- KMID: 2298026
- Korean Circ J.
- 2000 Aug;30(8):980-988.
- doi: 10.4070/kcj.2000.30.8.980
BACKGROUND: An increase of the extracellular K+concentrations up to about 8 mM in the isolated vessels causes relaxation in pre-contracted state. In order to elucidate the mechanisms of K+induced relaxation... -
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- Transport of Tetraethylammonium in Renal Cortical Endosomes of Cadmium-Intoxicated Rats
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Park HS, Kim KR, Park YS
- KMID: 1614854
- Korean J Physiol Pharmacol.
- 2002 Feb;6(1):21-26.
Effects of cadmium (Cd) intoxication on renal endosomal accumulation of organic cations (OC ) were studied in rats using 14C-tetraethylammnium (TEA) as a substrate. Cd intoxication was induced by s.c.... -
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- K+ -ATP - Channel Opener as a Potential Treatment for Erectile Dysfunction
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Moon DG, Byun HS, Kim JJ
- KMID: 2298846
- Korean J Androl.
- 1998 Jun;16(1):41-48.
PURPOSE: Intracavernous injection of PGE1 or papaverine is widely used in the diagnosis and treatment of erectile dysfunction. However, these drugs have several side effects such as pain, priapism, and... -
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- Taurine relaxes human radial artery through potassium channel opening action
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Ulusoy KG, Kaya E, Karabacak , Seyrek M, Duvan I, Yildirim V, Yildiz O
- KMID: 2395256
- Korean J Physiol Pharmacol.
- 2017 Nov;21(6):617-623.
- doi: 10.4196/kjpp.2017.21.6.617
The vascular actions and mechanisms of taurine were investigated in the isolated human radial artery (RA). RA rings were suspended in isolated organ baths and tension was recorded isometrically. First,... -
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- Effects of Calcium and Potassium Channel Blockers on Local Anesthetics-Induced Relaxation in Rat Thoracic Aortic Rings
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Kim HG, Park SS, Park JW
- KMID: 1934355
- Korean J Anesthesiol.
- 1995 Mar;28(3):376-384.
- doi: 10.4097/kjae.1995.28.3.376
This study was designed to evaluate the effects of calcium and potassium channel blockers on local anesthetics-induced vascular relaxation of isolated rat thoracic aorta. In the presence of lidocaine and... -
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- The Effect of Hypoxia on the Release of Endothelium-derived Relaxing Factor in Rabbit Thoracic Aorta
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Choi SS
- KMID: 2062943
- Korean J Thorac Cardiovasc Surg.
- 2009 Oct;42(5):588-596.
BACKGROUND: To clarify the effect of hypoxia on vascular contractility, we tried to show whether hypoxia induced the release of endothelium-derived relaxing factor (EDRF) and the nature of the underlying... -
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- Possible Involvement of Ca2+ Activated K+ Channels, SK Channel, in the Quercetin-Induced Vasodilatation
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Nishida S, Satoh H
- KMID: 1982569
- Korean J Physiol Pharmacol.
- 2009 Oct;13(5):361-365.
- doi: 10.4196/kjpp.2009.13.5.361
Effects of quercetin, a kind of flavonoids, on the vasodilating actions were investigated. Among the mechanisms for quercetin-induced vasodilatation in rat aorta, the involvement with the Ca2+ activated K+ (KCa)... -
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- Effect of K+-channel blockers on the muscarinic- and A|1-adenosine-receptor coupled regulation of electrically evoked acetylcholine release in the rat hippocampus
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Yu BS, Kim DK, Choi BK
- KMID: 1562314
- Korean J Physiol Pharmacol.
- 1998 Apr;2(2):147-154.
It was attempted to clarify the participation of K+ channels in the post-receptor mechanisms of the muscarinic and A1-adenosine receptor-mediated control of acetylcholine (ACh) release in the present study. Slices from the rat... -
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- Effects of Potassium Channel Modulators on Contractile Responses of Isolated Rat Vas Deferens to Field Stimulation
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Baik YH, Kim YM, Rhu BS
- KMID: 1973325
- Chonnam Med J.
- 2002 Mar;38(1):17-23.
Apart from regulating the resting membrane potential, K+ channels might also participate in cellular activity in response to endogenous neurotransmitters and exogenous agents. K+ channel modulators including 4 - aminopyridine... -
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- Potassium Currents in Isolated Deiters' Cells of Guinea Pig
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Chung JW, Nam EC, Kim WT, Youm JB, Leem CH
- KMID: 2285482
- Korean J Physiol Pharmacol.
- 2013 Dec;17(6):537-546.
- doi: 10.4196/kjpp.2013.17.6.537
Deiters' cells are the supporting cells in organ of Corti and are suggested to play an important role in biochemical and mechanical modulation of outer hair cells. We successfully isolated... -
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