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Evaluation of Protective Immunity of Peptide Vaccines Composed of a 15-mer N-terminal Matrix Protein 2 and a Helper T-Cell Epitope Derived from Influenza A Virus

Kim JK, Cheong S, Lee MK

The matrix protein 2 of influenza A virus (IFAV) has a relatively conserved ectodomain (M2e) composed of 23 amino acids, and M2e-based vaccines have been suggested to induce broad protective...
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Circulating CCR7(lo)PD-1(hi) Follicular Helper T Cells Indicate Disease Activity and Glandular Inflammation in Patients with Primary Sjögren's Syndrome

Kim JW, Lee J, Hong SM, Lee J, Cho ML, Park SH

Since primary Sjögren's syndrome (pSS) is an autoummune disease of B cell hyperactivity and pathologic autoantibody response, follicular helper T (Tfh) cells and follicular regulatory T (Tfr) cells are suggested...
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MicroRNA-mediated Regulation of the Development and Functions of Follicular Helper T cells

Lee J, Park H, Eom J, Kang SG

The germinal center reaction is a key event of humoral immunity, providing long-lived immunological memory. Follicular helper T (T(FH)) cells are a specialized subset of CD4⁺ T cells located in...
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T helper cell subsets and related cytokines in infertile women undergoing in vitro fertilization before and after seminal plasma exposure

Azad M, Keshtgar S, Jahromi BN, Kanannejad Z, Gharesi-Fard B

OBJECTIVE: In vitro fertilization (IVF) is a well-known method for the treatment of infertility. The present study aimed to compare the differences between infertile women with successful and unsuccessful IVF...
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Immunohistochemical Analysis of Interleukin-17 Producing T Helper Cells and Regulatory T Cells Infiltration in Annular Erythema Associated with Sjogren's Syndrome

Itoi S, Tanemura A, Tani M, Kitaba S, Terao M, Murota H, Oiso N, Katayama I

BACKGROUND: Peculiar erythema known as annular erythema associated with Sjogren's syndrome (AESS) can be differentiated from autoimmune annular erythema and subacute cutaneous lupus erythematosus, both clinically and histologically. However, there...
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Insights into the Role of Follicular Helper T Cells in Autoimmunity

Park HJ, Kim DH, Lim SH, Kim WJ, Youn J, Choi YS, Choi JM

Follicular helper T (TFH) cells are recently highlighted as their crucial role for humoral immunity to infection as well as their abnormal control to induce autoimmune disease. During an infection,...
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Innate lymphoid cells and cytokines of the novel subtypes of helper T cells in asthma

Sherkat R, Yazdani R, Ganjalikhani Hakemi M, Homayouni , Farahani R, Hosseini M, Rezaei A

BACKGROUND: In this study, the expression of interleukin-9 (IL-9), IL-17, IL-22, and IL-25 genes that might be the potential predisposing factors for asthma as well as count of innate lymphoid...
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CD4+ T Helper Cells Engineered to Produce IL-10 Reverse Allergen-induced Airway Hyperreactivity and Inflammation

Oh JW, Dekruyff R, Umetsu D

  • KMID: 1570680
  • Pediatr Allergy Respir Dis.
  • 2000 Dec;10(4):279-289.
PURPOSE: Asthma is characterized by airway hyperreactivity to a variety of specific and nonspecific stimuli, by chronic airway inflammation with pulmonary eosinophilia, by mucus hypersecretion, and by increased serum IgE...
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Polarization of T helper Cells Depends on the Presence of Antigen Presentation

Kim JG, Hahn YS

  • KMID: 1550784
  • Korean J Immunol.
  • 1999 Jun;21(2):137-145.
There are strong evidences suggesting that Thl and Th2 lymphocytes develop from the same Thlymphocyte precursor under the influence of environmental or genetic factors acting at the level of antigen...
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alphabeta T - Helper Cell Dependency in the Development of Anticardiolipin and Anti - beta2 Glycoprotein I Antibodies in MRL / MP - lpr / lpr Mice

Kang IS

  • KMID: 2082994
  • Korean J Immunol.
  • 1997 Sep;19(3):301-306.
No abstract available.
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